Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.67 |
| ▸ | MEN1 | O00255 | 6/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | TGM2 | P21980 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | NAMPT | P43490 | 1/20 | 0.56 |
| ▸ | MITF | O75030 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | MYOC | Q99972 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1102071 | 0.85 | KMT2A (0.71) | KMT2AMEN1POLBTGM2NPC1 | |
| SCHEMBL3189929 | 0.83 | KMT2A (0.69) | KMT2AMEN1POLBTGM2NPC1 | |
| Hydrochloric Acid SCHEMBL27491393 | 0.83 | KMT2A (0.69) | KMT2AMEN1POLBTGM2NPC1 | |
| SCHEMBL6659086 | 0.81 | KMT2A (0.67) | KMT2AMEN1POLBTGM2NPC1 | |
| SCHEMBL1177730 | 0.80 | MEN1 (1.00) | KMT2AMEN1POLBTGM2NPC1 | |
| SCHEMBL6302157 | 0.80 | MEN1 (1.00) | KMT2AMEN1POLBTGM2NPC1 | |
| SCHEMBL147358 | 0.79 | ALDH1A1 (0.64) | KMT2AMEN1POLBTGM2NPC1 | |
| SCHEMBL1740370 | 0.79 | KMT2A (0.63) | KMT2AMEN1POLBTGM2NPC1 | |
| SCHEMBL31598561 | 0.79 | KMT2A (0.62) | KMT2AMEN1POLBTGM2NPC1 | |
| SCHEMBL5005472 | 0.79 | KMT2A (0.62) | KMT2AMEN1POLBTGM2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097413-A1 | 2-[(2-SUBSTITUTED)-IND0LIZIN-3-YL]-2-OXO-ACETAMIDE DERIVATIVES AS ANTIFUNGAL AGENTS | F2G Limited (GB) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008062182-A1 | 2- [ (2-SUBSTITUTED) -IND0LIZIN-3-YL] -2-OXO-ACETAMIDE DERIVATIVES AS ANTIFUNGAL AGENTS | F2G LTD (GB) | 2008-05-29 | — | — | WO | disclosed |