Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | TGM2 | P21980 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27499998 | 0.98 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL5528163 | 0.90 | MEN1 (0.62) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL5527089 | 0.90 | MAPT (0.69) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL16573282 | 0.85 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL14633632 | 0.84 | ALDH1A1 (0.79) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL6301912 | 0.84 | ALDH1A1 (0.79) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL1102071 | 0.82 | KMT2A (0.71) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL7776355 | 0.82 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL11075336 | 0.81 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL458335 | 0.81 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 173 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115819305-B | Continuous preparation process of p-nitrophenyl thiourea | 浙江迪邦化工有限公司 | 2024-06-07 | — | — | CN | claimed |
| CN-116804070-A | Polyacrylamide polymer for movable gel, and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-09-26 | — | — | CN | claimed |
| CN-116514834-A | Chiral alpha-CF 2 H spiro [ pyrrolidine-pyrazolones]Synthesis method of class compound | 深圳市图微安创科技开发有限公司 | 2023-08-01 | — | — | CN | claimed |
| CN-115819305-A | Continuous preparation process of p-nitrophenylthiourea | 浙江迪邦化工有限公司 | 2023-03-21 | — | — | CN | claimed |
| EP-3830318-A1 | ELECTROPLATING BATH FOR DEPOSITING A BLACK ALLOY, METHOD FOR THE ELECTROCHEMICAL DEPOSITION OF A BLACK ALLOY ON A SUBSTRATE, A BLACK ALLOY AND AN ARTICLE COATED WITH SUCH BLACK ALLOY | COVENTYA S.p.A. (IT) | 2021-06-09 | — | — | EP | claimed |
| WO-2020025448-A1 | ELECTROPLATING BATH FOR DEPOSITING A BLACK ALLOY, METHOD FOR THE ELECTROCHEMICAL DEPOSITION OF A BLACK ALLOY ON A SUBSTRATE, A BLACK ALLOY AND AN ARTICLE COATED WITH SUCH BLACK ALLOY | COVENTYA S.P.A. (IT) | 2020-02-06 | — | — | WO | claimed |
| EP-3604626-A1 | ELECTROPLATING BATH FOR DEPOSITING A BLACK ALLOY, METHOD FOR THE ELECTROCHEMICAL DEPOSITION OF A BLACK ALLOY ON A SUBSTRATE, A BLACK ALLOY AND AN ARTICLE COATED WITH SUCH BLACK ALLOY | COVENTYA S.p.A. (IT) | 2020-02-05 | — | — | EP | claimed |
| CN-107056666-B | A kind of organogel compound of 4- nitrobenzenes thiocarbamide and preparation method thereof, gel and application | 信阳师范学院 | 2018-09-14 | — | — | CN | claimed |
| CN-107056666-A | A kind of organogel compound of 4 nitrobenzene thiocarbamide and preparation method thereof, gel and application | 信阳师范学院 | 2017-08-18 | — | — | CN | claimed |
| CN-103373969-A | Phenyl imidazole ring-substituted amide compounds as well as preparation method and application for same | SHANGHAI INST ORGANIC CHEM | 2013-10-30 | — | — | CN | claimed |
| CN-102079732-B | Method for synthesizing 2-amino-4-methylthiazole-5-carboxylate and derivatives thereof | UNIV XI AN JIAOTONG | 2013-03-13 | — | — | CN | claimed |
| CN-102079732-A | Method for synthesizing 2-amino-4-methylthiazole-5-carboxylate and derivatives thereof | UNIV XI AN JIAOTONG | 2011-06-01 | — | — | CN | claimed |
| CN-101687816-A | Triaminopyrimidine derivatives as the CDC25 inhibitors of phosphatases | IPSEN PHARMA SAS | 2010-03-31 | — | — | CN | claimed |
| CN-100360932-C | Reagent for detecting mercury ion in water and its preparation method | UNIV XIAMEN (CN) | 2008-01-09 | — | — | CN | claimed |
| CN-1752750-A | Reagent for detecting mercury ion in water and its preparation method | UNIV XIAMEN (CN) | 2006-03-29 | — | — | CN | claimed |
| EP-1148048-B1 | Polyaromatic compounds for treating herpes viral infections | PHARMACIA & UPJOHN CO LLC (US) | 2005-06-29 | — | — | EP | claimed |
| US-5236633-A | Blend of transparent polymer, thiourea and copper compounds | JUJO PAPER CO., LTD. (JP) | 1993-08-17 | — | — | US | claimed |
| US-4363913-A | Preparation of 2-aminobenzothiazoles | EASTMAN KODAK COMPANY (US) | 1982-12-14 | — | — | US | claimed |
| US-4264710-A | AN ETHYLENICALLY UNSATURATED COMPOUND, AND A PHOTOPOLYMERIZATION INIATOR | FUJI PHOTO FILM CO., LTD. (JP) | 1981-04-28 | — | — | US | claimed |
| CN-119390872-A | P-nitrobenzoyl thiourea chitosan derivative and application thereof | 新疆大学 | 2025-02-07 | — | — | CN | disclosed |
| CN-119390872-A | P-nitrobenzoyl thiourea chitosan derivative and application thereof | 新疆大学 | 2025-02-07 | — | — | CN | disclosed |
| CN-107629022-B | Antibacterial synergist and preparation method and application thereof | 上海医药工业研究院 | 2024-11-12 | — | — | CN | disclosed |
| CN-118619952-A | Aloperine derivative, preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2024-09-10 | — | — | CN | disclosed |
| CN-115819305-B | Continuous preparation process of p-nitrophenyl thiourea | 浙江迪邦化工有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-115819305-B | Continuous preparation process of p-nitrophenyl thiourea | 浙江迪邦化工有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-115819305-B | Continuous preparation process of p-nitrophenyl thiourea | 浙江迪邦化工有限公司 | 2024-06-07 | — | — | CN | disclosed |
| US-11993573-B2 | Chromane-substituted, tetrahydroquinoline-substituted and thiochromane-substituted heteroarotinoids as anti-cancer agents | THE BOARD OF REGENTS FOR OKLAHOMA STATE UNIVERSITY (US) | 2024-05-28 | — | — | US | disclosed |
| EP-4333843-A1 | BITHIAZOL DERATIVES AS INHIBITORS OF LYSYL OXIDASES | University of South Carolina (US) | 2024-03-13 | — | — | EP | disclosed |
| US-20240075015-A1 | Inhibitors of Lysyl Oxidases | UNIVERSITY OF SOUTH CAROLINA | 2024-03-07 | — | — | US | disclosed |
| CN-117545480-A | Dithiazole derivatives as inhibitors of lysyl oxidase | 南卡罗来纳大学 | 2024-02-09 | — | — | CN | disclosed |
| CN-115109048-B | (hetero) aryl amide compound | 中国药科大学 | 2023-12-08 | — | — | CN | disclosed |
| CN-116804070-A | Polyacrylamide polymer for movable gel, and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-09-26 | — | — | CN | disclosed |
| CN-116768770-A | Diaryl thiourea compound and application thereof | 上海交通大学医学院 | 2023-09-19 | — | — | CN | disclosed |
| CN-114249702-B | N-aryl- [2,4 '-dithiazole ] -2' -amine compound and preparation and application thereof | 沈阳药科大学 | 2023-09-05 | — | — | CN | disclosed |
| US-20230263167-A1 | METHOD OF PREPARING A BISMUTH SULFIDE PARTICLE CONTAINING ANTIBACTERIAL COMPOSITION | IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) | 2023-08-24 | — | — | US | disclosed |
| US-11712437-B2 | Inhibitors of lysyl oxidases | UNIVERSITY OF SOUTH CAROLINA (US) | 2023-08-01 | — | — | US | disclosed |
| US-11712437-B2 | Inhibitors of lysyl oxidases | UNIVERSITY OF SOUTH CAROLINA (US) | 2023-08-01 | — | — | US | disclosed |
| US-11712437-B2 | Inhibitors of lysyl oxidases | UNIVERSITY OF SOUTH CAROLINA (US) | 2023-08-01 | — | — | US | disclosed |
| CN-116514834-A | Chiral alpha-CF 2 H spiro [ pyrrolidine-pyrazolones]Synthesis method of class compound | 深圳市图微安创科技开发有限公司 | 2023-08-01 | — | — | CN | disclosed |
| US-11700855-B2 | Method for preventing or reducing growth of a microorganism on a surface | IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) | 2023-07-18 | — | — | US | disclosed |
| WO-2023121022-A1 | NOVEL LEUKOTRIENE B4 RECEPTOR INHIBITORS AND USE THEREOF | 이화여자대학교 산학협력단 | 2023-06-29 | — | — | WO | disclosed |
| CN-111704620-B | [3,2' ] -pyrrolidine chiral spiro oxindole skeleton compound, and preparation method and application thereof | 中国科学院成都有机化学有限公司 | 2023-05-23 | — | — | CN | disclosed |
| US-20230129765-A1 | METHOD FOR PRODUCING POLYTHIOETHER COMPOUND | DAICEL CORPORATION (JP) | 2023-04-27 | — | — | US | disclosed |
| CN-115819305-A | Continuous preparation process of p-nitrophenylthiourea | 浙江迪邦化工有限公司 | 2023-03-21 | — | — | CN | disclosed |
| CN-115819305-A | Continuous preparation process of p-nitrophenylthiourea | 浙江迪邦化工有限公司 | 2023-03-21 | — | — | CN | disclosed |
| CN-115819305-A | Continuous preparation process of p-nitrophenylthiourea | 浙江迪邦化工有限公司 | 2023-03-21 | — | — | CN | disclosed |
| EP-4108705-A1 | METHOD FOR PRODUCING POLYTHIOETHER COMPOUND | Daicel Corporation (JP) | 2022-12-28 | — | — | EP | disclosed |
| US-20220378753-A1 | NOVEL INHIBITORS OF LYSYL OXIDASES | UNIVERSITY OF SOUTH CAROLINA (US) | 2022-12-01 | — | — | US | disclosed |
| WO-2022240476-A1 | BITHIAZOL DERATIVES AS INHIBITORS OF LYSYL OXIDASES | UNIVERSITY OF SOUTH CAROLINA (US) | 2022-11-17 | — | — | WO | disclosed |
| CN-115135697-A | Process for producing polythioether compound | 株式会社大赛璐 | 2022-09-30 | — | — | CN | disclosed |
| CN-114249702-A | N-aryl- [2,4 '-bithiazole ] -2' -amine compound and preparation and application thereof | 沈阳药科大学 | 2022-03-29 | — | — | CN | disclosed |
| CN-113278149-A | Process for producing polythioether compound | 株式会社大赛璐 | 2021-08-20 | — | — | CN | disclosed |
| EP-3830318-A1 | ELECTROPLATING BATH FOR DEPOSITING A BLACK ALLOY, METHOD FOR THE ELECTROCHEMICAL DEPOSITION OF A BLACK ALLOY ON A SUBSTRATE, A BLACK ALLOY AND AN ARTICLE COATED WITH SUCH BLACK ALLOY | COVENTYA S.p.A. (IT) | 2021-06-09 | — | — | EP | disclosed |
| US-20210061670-A1 | METHOD FOR PREVENTING OR REDUCING GROWTH OF A MICROORGANISM ON A SURFACE | IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) | 2021-03-04 | — | — | US | disclosed |
| US-10934176-B2 | Methods of degrading organic pollutants and preventing or treating microbe using Bi2S3-CdS particles | IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) | 2021-03-02 | — | — | US | disclosed |
| CN-211963342-U | Filtration equipment of p-nitrothiosemicarbazide | 杭州布朗生物医药科技有限公司 | 2020-11-20 | — | — | CN | disclosed |
| CN-111704620-A | High-optical-purity [3, 2' ] -pyrrolidine chiral spiro-oxoindole skeleton compound, and preparation method and application thereof | 中国科学院成都有机化学有限公司 | 2020-09-25 | — | — | CN | disclosed |
| US-20200102228-A1 | METHODS OF DEGRADING ORGANIC POLLUTANTS AND PREVENTING OR TREATING MICROBE USING Bi2S3-CdS PARTICLES | IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) | 2020-04-02 | — | — | US | disclosed |
| WO-2020025448-A1 | ELECTROPLATING BATH FOR DEPOSITING A BLACK ALLOY, METHOD FOR THE ELECTROCHEMICAL DEPOSITION OF A BLACK ALLOY ON A SUBSTRATE, A BLACK ALLOY AND AN ARTICLE COATED WITH SUCH BLACK ALLOY | COVENTYA S.P.A. (IT) | 2020-02-06 | — | — | WO | disclosed |
| EP-3604626-A1 | ELECTROPLATING BATH FOR DEPOSITING A BLACK ALLOY, METHOD FOR THE ELECTROCHEMICAL DEPOSITION OF A BLACK ALLOY ON A SUBSTRATE, A BLACK ALLOY AND AN ARTICLE COATED WITH SUCH BLACK ALLOY | COVENTYA S.p.A. (IT) | 2020-02-05 | — | — | EP | disclosed |
| CN-107963617-B | A kind of production method and system of nitrosyl sulfuric acid | ZHEJIANG DIBANG CHEMICAL CO., LTD. (CN) | 2019-11-01 | — | — | CN | disclosed |
| CN-109971202-A | A kind of benzothiazoles dispersion dyes monomer compound and its synthetic method and application | 浙江迪邦化工有限公司 | 2019-07-05 | — | — | CN | disclosed |
| US-10105687-B1 | Heterostructured Bi2S3—ZnS photocatalysts and methods thereof | IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) | 2018-10-23 | — | — | US | disclosed |
| CN-107056666-B | A kind of organogel compound of 4- nitrobenzenes thiocarbamide and preparation method thereof, gel and application | 信阳师范学院 | 2018-09-14 | — | — | CN | disclosed |
| CN-107056666-B | A kind of organogel compound of 4- nitrobenzenes thiocarbamide and preparation method thereof, gel and application | 信阳师范学院 | 2018-09-14 | — | — | CN | disclosed |
| CN-107056666-B | A kind of organogel compound of 4- nitrobenzenes thiocarbamide and preparation method thereof, gel and application | 信阳师范学院 | 2018-09-14 | — | — | CN | disclosed |
| CN-107963617-A | The production method and system of a kind of nitrosyl sulfuric acid | 浙江迪邦化工有限公司 | 2018-04-27 | — | — | CN | disclosed |
| CN-107056666-A | A kind of organogel compound of 4 nitrobenzene thiocarbamide and preparation method thereof, gel and application | 信阳师范学院 | 2017-08-18 | — | — | CN | disclosed |
| CN-107056666-A | A kind of organogel compound of 4 nitrobenzene thiocarbamide and preparation method thereof, gel and application | 信阳师范学院 | 2017-08-18 | — | — | CN | disclosed |
| EP-2700636-B1 | PROCESS FOR PREPARING EPISULFIDE COMPOUNDS | ASAHI CHEMICAL IND (JP) | 2017-08-02 | — | — | EP | disclosed |
| US-20170020900-A1 | METHODS FOR SCREENING ANTIMICROBIAL AND ANTIVIRAL COMPOUNDS AND USES THEREOF | NIH - DEITR | 2017-01-26 | — | — | US | disclosed |
| US-9359324-B2 | Process for preparing episulfide compounds | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2016-06-07 | — | — | US | disclosed |
| CN-105524013-A | Preparation method of 4,5-disubstituted-2-substituted aminothiazole compound | UNIV ZHEJIANG | 2016-04-27 | — | — | CN | disclosed |
| US-9301940-B2 | Methods for screening antimicrobial and antiviral compounds and uses thereof | THE GENERAL HOSPITAL CORPORATION (US) | 2016-04-05 | — | — | US | disclosed |
| US-9301940-B2 | Methods for screening antimicrobial and antiviral compounds and uses thereof | THE GENERAL HOSPITAL CORPORATION (US) | 2016-04-05 | — | — | US | disclosed |
| US-9150561-B2 | Thiazole derivatives and use thereof | MERCK SERONO S.A. (CH) | 2015-10-06 | — | — | US | disclosed |
| CN-103159695-B | HIV can be suppressed to copy and to effective thiazole compound of resistance HIV virus strain and its production and use | CAPITAL NORMAL UNIVERSITY (CN) | 2015-08-12 | — | — | CN | disclosed |
| US-20150197501-A1 | Process for Preparing Episulfide Compounds | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2015-07-16 | — | — | US | disclosed |
| US-9051293-B2 | Process for preparing episulfide compounds | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2015-06-09 | — | — | US | disclosed |
| CN-104610222-A | Process for preparing episulfide compounds | ASAHI KASEI CHEMICALS CORP | 2015-05-13 | — | — | CN | disclosed |
| US-20140228365-A1 | THIAZOLE DERIVATIVES AND USE THEREOF | MERCK SERONO S.A. (CH) | 2014-08-14 | — | — | US | disclosed |
| CN-102603726-B | 5-(2-aminothiazole-4-yl) benzofuranol etheric compound with herbicidal activity and preparation method | HUNAN RES INST CHEMICAL IND | 2014-08-13 | — | — | CN | disclosed |
| US-8802861-B2 | Thiazole derivatives and use thereof | MERCK SERONO SA (CH) | 2014-08-12 | — | — | US | disclosed |
| US-20140107350-A1 | Process for Preparing Episulfide Compounds | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2014-04-17 | — | — | US | disclosed |
| EP-2700636-A1 | PROCESS FOR PREPARING EPISULFIDE COMPOUNDS | Asahi Kasei Chemicals Corporation (JP) | 2014-02-26 | — | — | EP | disclosed |
| CN-103476764-A | Process for producing episulfide compound | ASAHI KASEI CHEMICALS CORP (JP) | 2013-12-25 | — | — | CN | disclosed |
| US-20130184258-A1 | Compositions Useful as Inhibitors of Voltage-Gated Sodium Channels | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2013-07-18 | — | — | US | disclosed |
| CN-103159695-A | Thiazole compound capable of restraining human immunodeficiency virus (HIV) replication and effective against drug-resistant HIV virus strains and preparation method and purpose thereof | UNIV CAPITAL NORMAL | 2013-06-19 | — | — | CN | disclosed |
| CN-102079732-B | Method for synthesizing 2-amino-4-methylthiazole-5-carboxylate and derivatives thereof | UNIV XI AN JIAOTONG | 2013-03-13 | — | — | CN | disclosed |
| US-8309543-B2 | Compositions useful as inhibitors of voltage-gated sodium channels | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-11-13 | — | — | US | disclosed |
| CN-101906083-B | Method for preparing 2-amino-6-nitrobenzothiazole | GUANGZHOU FANGDA SCIENCE AND TECHNOLOGY CO LTD | 2012-10-03 | — | — | CN | disclosed |
| US-20120238578-A1 | COMPOSITIONS USEFUL AS INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-09-20 | — | — | US | disclosed |
| CN-102603726-A | 5-(2-aminothiazole-4-yl) benzofuranol etheric compound with herbicidal activity and preparation method | HUNAN RES INST CHEMICAL IND | 2012-07-25 | — | — | CN | disclosed |
| CN-102010406-B | 4-(benzofuran-5-yl)-2-aromatic aminothiazole and preparation method and application thereof | UNIV HUNAN | 2012-07-04 | — | — | CN | disclosed |
| US-8202861-B2 | Drugs for various disorders | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-06-19 | — | — | US | disclosed |
| CN-1926121-B | Thiazole derivatives and uses thereof | MERCK SERONO SA | 2012-06-13 | — | — | CN | disclosed |
| US-8153655-B2 | Compositions useful as inhibitors of voltage-gated sodium channels | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-04-10 | — | — | US | disclosed |
| WO-2012038904-A1 | NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |
| US-20120059163-A1 | Non-linear opticaly active molecules, their synthesis, and use | OPTIMER PHOTONICS, INC. (US) | 2012-03-08 | — | — | US | disclosed |
| EP-2332912-A1 | Heteroarylaminosulfonylphenylderivates for use as sodium or calcium channel blockers in the treatment of pain | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-06-15 | — | — | EP | disclosed |
| EP-2327701-A1 | Heteroarylaminosulfonylphenyl derivatives for use as sodium or calcium channel blockers in the treatment of pain | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-06-01 | — | — | EP | disclosed |
| CN-102079732-A | Method for synthesizing 2-amino-4-methylthiazole-5-carboxylate and derivatives thereof | UNIV XI AN JIAOTONG | 2011-06-01 | — | — | CN | disclosed |
| US-20110105436-A1 | HETEROARYL COMPOUNDS, COMPOSITIONS, AND METHODS OF USE IN CANCER TREATMENT | AUCKLAND UNISERVICES LIMITED (NZ) | 2011-05-05 | — | — | US | disclosed |
| CN-102010406-A | 4-(benzofuran-5-yl)-2-aromatic aminothiazole and preparation method and application thereof | UNIV HUNAN | 2011-04-13 | — | — | CN | disclosed |
| CN-101906083-A | Method for preparing 2-amino-6-nitrobenzothiazole | GUANGZHOU FANGDA SCIENCE AND TECHNOLOGY CO LTD | 2010-12-08 | — | — | CN | disclosed |
| US-20100298340-A1 | Thiazol-Guanidine Derivatives Useful As A (Beta)-Related Pathologies | ASTRAZENECA AB (SE) | 2010-11-25 | — | — | US | disclosed |
| US-20100216852-A1 | METHODS FOR SCREENING ANTIMICROBIAL AND ANTIVIRAL COMPOUNDS AND USES THEREOF | THE GENERAL HOSPITAL CORPORATION | 2010-08-26 | — | — | US | disclosed |
| US-20100216852-A1 | METHODS FOR SCREENING ANTIMICROBIAL AND ANTIVIRAL COMPOUNDS AND USES THEREOF | THE GENERAL HOSPITAL CORPORATION | 2010-08-26 | — | — | US | disclosed |
| CN-101768134-A | 2-imido-3-(substituted phenyl)-4-methyl-5-acetyl-4-thiazoline and synthesis method thereof | ZHEJIANG PHARMACEUTICAL COLLEG | 2010-07-07 | — | — | CN | disclosed |
| US-20100087479-A1 | Compositions Useful as Inhibitors of Voltage-Gated Sodium Channels | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2010-04-08 | — | — | US | disclosed |
| CN-101687816-A | Triaminopyrimidine derivatives as the CDC25 inhibitors of phosphatases | IPSEN PHARMA SAS | 2010-03-31 | — | — | CN | disclosed |
| US-20100048641-A1 | Use of Adenosine A1 and/or Dual A1/2ab Agonists for Production of Medicaments for Treating Diseases | BAYER HEALTHCARE AG LAW AND PATENTS,PATENTS AND LICENSING (DE) | 2010-02-25 | — | — | US | disclosed |
| CN-101643458-A | Heteroarylaminosulfonylphenyl derivatives for use as sodium or calcium channel blockers in the treatment of pain | VERTEX PHARMA US | 2010-02-10 | — | — | CN | disclosed |
| US-7615563-B2 | Compositions useful as inhibitors of voltage-gated sodium channels | VERTEX PHARMACEUTICALS INCORPORATED | 2009-11-10 | — | — | US | disclosed |
| WO-2009114552-A1 | HETEROARYL COMPOUNDS, COMPOSITIONS, AND METHODS OF USE IN CANCER TREATMENT | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2009-09-17 | — | — | WO | disclosed |
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| EP-1653961-A4 | INHIBITORS OF AKT ACTIVITY | SMITHKLINE BEECHAM CORP (US) | 2009-04-01 | — | — | EP | disclosed |
| US-20090029998-A1 | Thiazole Derivatives and Use Thereof | APPLIED RESEARCH SYSTEM ARS HOLDING N.V. (NL) | 2009-01-29 | — | — | US | disclosed |
| EP-2010508-A1 | THIAZOL-GUANIDINE DERIVATIVES USEFUL AS A (BETA)- RELATED PATHOLOGIES | AstraZeneca AB (SE) | 2009-01-07 | — | — | EP | disclosed |
| US-20080269300-A1 | Substituted Phenylaminothiazoles and Use Thereof | BAYER HEALTHCARE AG (DE) | 2008-10-30 | — | — | US | disclosed |
| US-20080255143-A1 | Inhibitors of Akt Activity | SMITHKLINE BEECHAM CORPORATION (PA) | 2008-10-16 | — | — | US | disclosed |
| CN-100422179-C | 2-amino-5-benzoylthiazole npy antagonists | HOFFMANN LA ROCHE (CH) | 2008-10-01 | — | — | CN | disclosed |
| US-20080227895-A1 | Fire retardant vinyl chloride-based resin composition and molded article thereof | MITSUBISHI PLASTICS, INC. (JP) | 2008-09-18 | — | — | US | disclosed |
| WO-2008066576-A2 | METHODS FOR SCREENING ANTIMICROBIAL AND ANTIVIRAL COMPOUNDS AND USES THEREOF | THE GENERAL HOSPITAL CORPORATION (US) | 2008-06-05 | — | — | WO | disclosed |
| CN-100360932-C | Reagent for detecting mercury ion in water and its preparation method | UNIV XIAMEN (CN) | 2008-01-09 | — | — | CN | disclosed |
| US-20080004415-A1 | Non-linear optically active molecules, their synthesis, and use | OPTIMER PHOTONICS, INC. (US) | 2008-01-03 | — | — | US | disclosed |
| EP-1658288-B1 | 2-AMINO-5-BENZOYLTHIAZOLE NPY ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2007-12-05 | — | — | EP | disclosed |
| WO-2007120096-A1 | THIAZOL-GUANIDINE DERIVATIVES USEFUL AS A (BETA)- RELATED PATHOLOGIES | ASTRAZENECA AB (SE) | 2007-10-25 | — | — | WO | disclosed |
| EP-1709019-B1 | THIAZOLE DERIVATIVES AND USE THEREOF | APPLIED RESEARCH SYSTEMS (AN) | 2007-08-08 | — | — | EP | disclosed |
| US-7250431-B2 | neuropeptide Y(NPY) receptor antagonists; useful in the treatment of obesity; such as 4-methoxy-N-{4-[5-(2-methyl-benzoyl)-thiazol-2-ylamino]-phenyl}-benzenesulfonamide | HOFFMANN-LA ROCHE INC. (US) | 2007-07-31 | — | — | US | disclosed |
| CN-1926121-A | Thiazole derivatives and uses thereof | APPLIED RESEARCH SYSTEMS (AN) | 2007-03-07 | — | — | CN | disclosed |
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |
| US-20070010671-A1 | Novel quinazoline derivatives and methods of treatment related to the use thereof | ARENA PHARMACEUTICALS, INC. | 2007-01-11 | — | — | US | disclosed |
| CN-1863785-A | Heteroarylaminosulfonylphenyl derivatives useful as sodium or calcium channel blockers in the treatment of pain | VERTEX PHARMA (US) | 2006-11-15 | — | — | CN | disclosed |
| CN-1852907-A | 2-amino-5-benzoylthiazole npy antagonists | HOFFMANN LA ROCHE (CH) | 2006-10-25 | — | — | CN | disclosed |
| EP-1709019-A2 | THIAZOLE DERIVATIVES AND USE THEREOF | Applied Research Systems ARS Holding N.V. (AN) | 2006-10-11 | — | — | EP | disclosed |
| EP-1673357-A2 | HETEROARYLAMINOSULFONYLPHENYL DERIVATIVES FOR USE AS SODIUM OR CALCIUM CHANNEL BLOCKERS IN THE TREATMENT OF PAIN | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2006-06-28 | — | — | EP | disclosed |
| EP-1658288-A1 | 2-AMINO-5-BENZOYLTHIAZOLE NPY ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-05-24 | — | — | EP | disclosed |
| EP-1653961-A1 | INHIBITORS OF AKT ACTIVITY | SMITHKLINE BEECHAM CORPORATION (US) | 2006-05-10 | — | — | EP | disclosed |
| CN-1752750-A | Reagent for detecting mercury ion in water and its preparation method | UNIV XIAMEN (CN) | 2006-03-29 | — | — | CN | disclosed |
| US-20060025415-A1 | Compositions useful as inhibitors of voltage-gated sodium channels | VERTEX PHARMACEUTICALS INCORPORATED | 2006-02-02 | — | — | US | disclosed |
| US-20060014874-A1 | Flame-resistant vinyl chlorride based resin composition and formed product therefrom | MITSUBISHI PLASTICS, INC. (JP) | 2006-01-19 | — | — | US | disclosed |
| US-6967205-B1 | Compounds with antibacterial and antiparasitic properties | NEW PHARMA RESEARCH SWEDEN AB (SE) | 2005-11-22 | — | — | US | disclosed |
| WO-2005068444-A2 | THIAZOLE DERIVATIVES AND USE THEREOF | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2005-07-28 | — | — | WO | disclosed |
| US-20050137190-A1 | Compositions useful as inhibitors of voltage-gated sodium channels | VERTEX PHARMACEUTICALS INCORPORATED | 2005-06-23 | — | — | US | disclosed |
| US-20050038089-A1 | neuropeptide Y(NPY) receptor antagonists; useful in the treatment of obesity; such as 4-methoxy-N-{4-[5-(2-methyl-benzoyl)-thiazol-2-ylamino]-phenyl}-benzenesulfonamide | HOFFMAN-LA ROCHE INC. | 2005-02-17 | — | — | US | disclosed |
| WO-2005013914-A2 | HETEROARYLAMINOSULFONYLPHENYL DERIVATIVES FOR USE AS SODIUM OR CALCIUM CHANNEL BLOCKERS IN THE TREATMENT OF PAIN | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2005-02-17 | — | — | WO | disclosed |
| WO-2005014592-A1 | 2-AMINO-5-BENZOYLTHIAZOLE NPY ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-02-17 | — | — | WO | disclosed |
| WO-2005011700-A1 | INHIBITORS OF Akt ACTIVITY | SMITHKLINE BEECHAM CORPORATION (US) | 2005-02-10 | — | — | WO | disclosed |
| EP-1085009-B1 | INDAN DERIVATIVES | NISSAN CHEMICAL IND LTD (JP) | 2004-11-10 | — | — | EP | disclosed |
| EP-1467981-A1 | 4(HETERO-) ARYL SUBSTITUTED (THIA-/OXA-/PYRA) ZOLES FOR INHIBITION OF TIE-2 | Kylix Pharmaceuticals B.V. (NL) | 2004-10-20 | — | — | EP | disclosed |
| US-20030158199-A1 | Novel compounds for inhibition of Tie-2 | KYLIX, B.V. (NL) | 2003-08-21 | — | — | US | disclosed |
| WO-2003062215-A1 | 4(HETERO-) ARYL SUBSTITUTED (THIA-/OXA-/PYRA) ZOLES FOR INHIBITION OF TIE-2 | KYLIX PHARMACEUTICALS B.V. (NL) | 2003-07-31 | — | — | WO | disclosed |
| EP-0934296-B1 | CHROMAN DERIVATIVES | NISSAN CHEMICAL IND LTD (JP) | 2003-06-04 | — | — | EP | disclosed |
| US-6486178-B1 | Indane derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2002-11-26 | — | — | US | disclosed |
| EP-1085009-A1 | INDAN DERIVATIVES | Nissan Chemical Industries, Ltd. (JP) | 2001-03-21 | — | — | EP | disclosed |
| CN-1054803-C | Polycarbonic acid ester resin layered products absorbing near-infrared and formed products made of same | DAICEL CHEM (JP) | 2000-07-26 | — | — | CN | disclosed |
| US-6066631-A | Chroman derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2000-05-23 | — | — | US | disclosed |
| WO-2000012492-A1 | BENZOXAZINE DERIVATIVES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2000-03-09 | — | — | WO | disclosed |
| EP-0934296-A1 | CHROMAN DERIVATIVES | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998004542-A1 | CHROMAN DERIVATIVES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-05 | — | — | WO | disclosed |
| CN-1035253-C | Pyranyl cyanoguanidine derivatives | SQUIBB & SONS INC (US) | 1997-06-25 | — | — | CN | disclosed |
| US-5514740-A | SHEET OR FILM HAVING CUPRIC SULFIDE DISPERSED THEREIN | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-07 | — | — | US | disclosed |
| EP-0282971-B1 | Substituted 2-aminobenzothiazoles and derivatives useful as cerebrovascular agents | WARNER LAMBERT CO (US) | 1994-12-28 | — | — | EP | disclosed |
| CN-1094354-A | Polycarbonate-based resin laminate of absorption near infrared ray and formed body thereof | DAICEL CHEM (JP) | 1994-11-02 | — | — | CN | disclosed |
| CN-1064272-A | PYRANYL CYANOGUANIDINE DERIVATIVES | SQUIBB & SONS INC (US) | 1992-09-09 | — | — | CN | disclosed |
| US-4971983-A | Use as anesthetics in surgery where a risk of cerebrovascular damage exists; e.g. riluzole | WARNER-LAMBERT COMPANY (US) | 1990-11-20 | — | — | US | disclosed |
| US-4918090-A | ADMINISTERING TO STROKE PATIENT | WARNER-LAMBERT COMPANY (US) | 1990-04-17 | — | — | US | disclosed |
| US-4826860-A | STROKES | WARNER-LAMBERT COMPANY (US) | 1989-05-02 | — | — | US | disclosed |
| EP-0282971-A2 | Substituted 2-aminobenzothiazoles and derivatives useful as cerebrovascular agents | WARNER-LAMBERT COMPANY (US) | 1988-09-21 | — | — | EP | disclosed |
| US-4719304-A | CYCLIZATION, BROMINE CATALYST | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-01-12 | — | — | US | disclosed |
| US-4665083-A | ANTIDEPRESSANT, ANTIEPILEPTIC, SPASMOLYTIC, ANTIPARKINSONIC | EGIS GYOGYSZERGYAR (HU) | 1987-05-12 | — | — | US | disclosed |
| US-4363913-A | Preparation of 2-aminobenzothiazoles | EASTMAN KODAK COMPANY (US) | 1982-12-14 | — | — | US | disclosed |
| US-4363913-A | Preparation of 2-aminobenzothiazoles | EASTMAN KODAK COMPANY (US) | 1982-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (25 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048641-A1 | Use of Adenosine A1 and/or Dual A1/2ab Agonists for Production of Medicaments for Treating Diseases | ADORA1, ADORA2B, ADORA2A | ALDH1A1 312/4885SMN1; SMN2 4135/4885MEN1 853/4885 |
| US-20030158199-A1 | Novel compounds for inhibition of Tie-2 | TIE1, TEK, KDR | ALDH1A1 1890/4885SMN1; SMN2 4623/4885MEN1 839/4885 |
| US-20240075015-A1 | Inhibitors of Lysyl Oxidases | LOXL1, LOXL2, LOXL4 | ALDH1A1 756/4885SMN1; SMN2 1642/4885MEN1 4801/4885 |
| US-20140228365-A1 | THIAZOLE DERIVATIVES AND USE THEREOF | PF4, TEC, PDGFRB | ALDH1A1 234/4885SMN1; SMN2 4287/4885MEN1 1164/4885 |
| US-20120238578-A1 | COMPOSITIONS USEFUL AS INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS | SCNN1G, KCNN3, KCNN2 | ALDH1A1 2811/4885SMN1; SMN2 524/4885MEN1 2329/4885 |
| US-20100298340-A1 | Thiazol-Guanidine Derivatives Useful As A (Beta)-Related Pathologies | GRN, MAPT, GUCY1B1 | ALDH1A1 1302/4885SMN1; SMN2 96/4885MEN1 3257/4885 |
| US-20100087479-A1 | Compositions Useful as Inhibitors of Voltage-Gated Sodium Channels | SCNN1G, KCNN3, KCNN2 | ALDH1A1 2811/4885SMN1; SMN2 524/4885MEN1 2329/4885 |
| US-20080269300-A1 | Substituted Phenylaminothiazoles and Use Thereof | PAH, TNNT2, VHL | ALDH1A1 739/4885SMN1; SMN2 4331/4885MEN1 2732/4885 |
| US-20110105436-A1 | HETEROARYL COMPOUNDS, COMPOSITIONS, AND METHODS OF USE IN CANCER TREATMENT | VHL, TP53, BECN1 | ALDH1A1 1737/4885SMN1; SMN2 2531/4885MEN1 3092/4885 |
| US-20050137190-A1 | Compositions useful as inhibitors of voltage-gated sodium channels | SCNN1G, KCNN3, KCNN2 | ALDH1A1 2811/4885SMN1; SMN2 524/4885MEN1 2329/4885 |
| US-20220378753-A1 | NOVEL INHIBITORS OF LYSYL OXIDASES | LOXL1, LOXL2, LOXL4 | ALDH1A1 1028/4885SMN1; SMN2 1679/4885MEN1 4832/4885 |
| US-20150197501-A1 | Process for Preparing Episulfide Compounds | TST, EPHX2, STS | ALDH1A1 405/4885SMN1; SMN2 3397/4885MEN1 3754/4885 |
| US-20070010671-A1 | Novel quinazoline derivatives and methods of treatment related to the use thereof | MCHR1, GPR119, MCHR2 | ALDH1A1 2069/4885SMN1; SMN2 1509/4885MEN1 647/4885 |
| US-20080255143-A1 | Inhibitors of Akt Activity | PI4KB, PIK3CA, AKT2 | ALDH1A1 4166/4885SMN1; SMN2 3299/4885MEN1 3151/4885 |
| US-20060025415-A1 | Compositions useful as inhibitors of voltage-gated sodium channels | SCNN1G, KCNN3, KCNN2 | ALDH1A1 2811/4885SMN1; SMN2 524/4885MEN1 2329/4885 |
| US-20170020900-A1 | METHODS FOR SCREENING ANTIMICROBIAL AND ANTIVIRAL COMPOUNDS AND USES THEREOF | ZC3HAV1, MAVS, EIF2AK2 | ALDH1A1 3829/4885SMN1; SMN2 3747/4885MEN1 4593/4885 |
| US-20090029998-A1 | Thiazole Derivatives and Use Thereof | PDGFRB, PDGFRA, TEC | ALDH1A1 174/4885SMN1; SMN2 1799/4885MEN1 1761/4885 |
| US-20130184258-A1 | Compositions Useful as Inhibitors of Voltage-Gated Sodium Channels | SCNN1G, KCNN3, KCNN2 | ALDH1A1 2811/4885SMN1; SMN2 524/4885MEN1 2329/4885 |
| US-20120059163-A1 | Non-linear opticaly active molecules, their synthesis, and use | INCENP, CYBA, ADCY5 | ALDH1A1 371/4885SMN1; SMN2 4522/4885MEN1 4480/4885 |
| US-20050038089-A1 | neuropeptide Y(NPY) receptor antagonists; useful in the treatment of obesity; such as 4-methoxy-N-{4-[5-(2-methyl-benzoyl)-thiazol-2-ylamino]-phenyl}-benzenesulfonamide | NPY5R, NPY1R, NPY4R | ALDH1A1 3138/4885SMN1; SMN2 2958/4885MEN1 1824/4885 |
| US-11712437-B2 | Inhibitors of lysyl oxidases | LOXL1, LOXL2, LOXL4 | ALDH1A1 864/4885SMN1; SMN2 1726/4885MEN1 4808/4885 |
| US-11993573-B2 | Chromane-substituted, tetrahydroquinoline-substituted and thiochromane-substituted heteroarotinoids as anti-cancer agents | HCCS, CDYL, CDYL2 | ALDH1A1 3983/4885SMN1; SMN2 4516/4885MEN1 2252/4885 |
| US-20080004415-A1 | Non-linear optically active molecules, their synthesis, and use | INCENP, CYBA, PAICS | ALDH1A1 378/4885SMN1; SMN2 4430/4885MEN1 4473/4885 |
| US-20140107350-A1 | Process for Preparing Episulfide Compounds | TST, EPHX2, STS | ALDH1A1 405/4885SMN1; SMN2 3397/4885MEN1 3754/4885 |
| US-20100216852-A1 | METHODS FOR SCREENING ANTIMICROBIAL AND ANTIVIRAL COMPOUNDS AND USES THEREOF | ZC3HAV1, MAVS, EIF2AK2 | ALDH1A1 3829/4885SMN1; SMN2 3747/4885MEN1 4593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.