SCHEMBL4440349

SCHEMBL4440349

NS(=O)(=O)C(Cl)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.46
CA1 P00915 6/20 0.43
CA2 P00918 6/20 0.43
CA9 Q16790 5/20 0.42
CA12 O43570 3/20 0.42
CA14 Q9ULX7 2/20 0.42
CA5A P35218 2/20 0.42
CA7 P43166 2/20 0.42
CA3 P07451 1/20 0.42
CA4 P22748 1/20 0.42
CA6 P23280 1/20 0.42
PLA2G7 Q13093 1/20 0.42
CA13 Q8N1Q1 1/20 0.42
CA5B Q9Y2D0 1/20 0.42
DPP4 P27487 2/20 0.40
F2 P00734 1/20 0.40
GBA1 P04062 1/20 0.40
SRC P12931 1/20 0.39
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5200599 0.81 TSHR (0.46) TSHRDPP4F2SRCALDH1A1
SCHEMBL3852183 0.80 TSHR (0.50) TSHRDPP4F2SRCALDH1A1
SCHEMBL1095271 0.78 TSHR (0.48) TSHRDPP4F2SRCALDH1A1
SCHEMBL21800163 0.77 CA1 (0.47) CA1CA2CA9CA12CA5A
SCHEMBL18028786 0.76 PTGES2 (0.44) CA1CA2CA9CA12CA14
SCHEMBL5200608 0.76 TSHR (0.46) TSHRDPP4SRCALDH1A1
SCHEMBL18028833 0.76 PTGES2 (0.44) CA1CA2CA9CA12CA14
SCHEMBL1792962 0.76 PTGES2 (0.44) CA1CA2CA9CA12CA14
SCHEMBL4589500 0.76 SRC (0.54) TSHRCA1CA2CA9CA12
SCHEMBL7695092 0.75 CA1 (0.46) CA1CA2CA9CA12CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111621484-A Modified hot start enzyme and preparation method thereof 济南国益生物科技有限公司 2020-09-04 CN claimed
CN-108467617-A Reactive surfaces coating with chemical decontamination and biocidal performance 美国消毒器公司 2018-08-31 CN claimed
CN-103889953-B Sulfamoylbenzamide derivatives as antiviral agents against hepatitis B virus infection 巴鲁﹒S﹒布隆伯格研究所 2016-06-08 CN claimed
CN-103889953-A Sulfamoylbenzamide Derivatives as Antiviral Agents Against Hepatitis B Virus Infection INST HEPATITIS & VIRUS RES 2014-06-25 CN claimed
CN-111621484-A Modified hot start enzyme and preparation method thereof 济南国益生物科技有限公司 2020-09-04 CN disclosed
CN-109999013-A Inhalable dry powder doses 普马特里克斯营业公司 2019-07-12 CN disclosed
CN-109641765-A Burn the draining recovery method and device of complete set of equipments 栗田工业株式会社 2019-04-16 CN disclosed
CN-109476850-A For increasing the method to the tolerance containing halogen oxidant of daiamid composition 罗地亚经营管理公司 2019-03-15 CN disclosed
CN-107596518-A Inhalable dry powder doses 普马特里克斯营业公司 2018-01-19 CN disclosed
CN-107531515-A Waste water treatment method for incineration plant 栗田工业株式会社 2018-01-02 CN disclosed
CN-107428566-A Method for operating reverse osmosis membrane treatment system and reverse osmosis membrane treatment system 栗田工业株式会社 2017-12-01 CN disclosed
CN-107406277-A Water treatment method and apparatus 栗田工业株式会社 2017-11-28 CN disclosed
WO-2014144871-A1 CYTOTOXIC AND ANTI-MITOTIC COMPOUNDS, AND METHODS OF USING THE SAME THE CENTRE FOR DRUG RESEARCH AND DEVELOPMENT (CA) 2014-09-18 WO disclosed
EP-2125675-A1 METHODS FOR GASSING EXPLOSIVES ESPECIALLY AT LOW TEMPERATURES Newcastle Innovation Limited (AU) 2009-12-02 EP disclosed
WO-2008083436-A1 METHODS FOR GASSING EXPLOSIVES ESPECIALLY AT LOW TEMPERATURES NEWCASTLE INNOVATION LIMITED (AU) 2008-07-17 WO disclosed
CN-1832922-A Sulfonyl-substituted N- (biarylmethyl) aminocyclopropanecarboxamides MERCK & CO INC (US) 2006-09-13 CN disclosed
CN-1303374-A Substituted indolinones, process for their preparation and their use as pharmaceutical compositions BOEHRINGER INGELHEIM PHARMA (DE) 2001-07-11 CN disclosed
US-5990353-A DEMETALLIZING AN ARYLSULFONAMIDE ALKALI METAL SALT WITH AN AROMATIC ISOCYANATE COMPOUND IN AT LEAST ONE SOLVENT; USE AS A COLOR DEVELOPER FOR A THERMAL RECORDING MATERIAL WITH IMPROVED OIL RESISTANCE AND NONPLASTICIZED YAMAMOTO CHEMICALS, INC. (JP) 1999-11-23 US disclosed
EP-0879816-A1 Process for producing arylsulfonylureide compounds Yamamoto Chemicals, Inc. (JP) 1998-11-25 EP disclosed
EP-0850227-A1 PYRIDAZIN-3-ONE DERIVATIVES, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-07-01 EP disclosed