SCHEMBL3852183

SCHEMBL3852183

O=S(=O)(C(Cl)c1ccccc1)C(Cl)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.50
SRC P12931 2/20 0.41
ALDH1A1 P00352 2/20 0.40
HSD17B10 Q99714 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
CYP2C19 P33261 1/20 0.39
CYP2D6 P10635 1/20 0.39
DPP4 P27487 2/20 0.38
F2 P00734 1/20 0.38
HTR6 P50406 1/20 0.38
LMNA P02545 2/20 0.37
MAPK1 P28482 1/20 0.37
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1095271 0.82 TSHR (0.48) TSHRSRCALDH1A1HSD17B10TDP1
SCHEMBL4589500 0.80 SRC (0.54) TSHRSRCALDH1A1TDP1CYP2C19
SCHEMBL5200608 0.80 TSHR (0.46) TSHRSRCALDH1A1HSD17B10TDP1
SCHEMBL5200599 0.80 TSHR (0.46) TSHRSRCALDH1A1HSD17B10TDP1
SCHEMBL4440349 0.80 TSHR (0.46) TSHRSRCALDH1A1DPP4F2
SCHEMBL11792813 0.77 TSHR (0.48) TSHRSRCALDH1A1HSD17B10TDP1
SCHEMBL31687206 0.75 CA2 (0.39) CYP2C19F2
SCHEMBL9449886 0.74 TSHR (0.74) TSHRSRCALDH1A1HSD17B10TDP1
SCHEMBL11574577 0.73 CA1 (0.47) TSHRSRCALDH1A1HSD17B10CYP2C19
SCHEMBL780336 0.72 CYP2C19 (0.52) TSHRSRCALDH1A1CYP2C19CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119700791-A Application of harpagoside in preparation of ionizing radiation injury protection drugs 中国医学科学院放射医学研究所 2025-03-28 CN disclosed
CN-119700790-A Novel therapeutic application of harpagoside 中国医学科学院放射医学研究所 2025-03-28 CN disclosed
US-10946075-B1 Radioprotection, radiomitigation and radiorecovery RADSYNERGY, LLC 2021-03-16 US disclosed
CN-105623384-A Ink carriers containing surface modified nanoparticles, phase change inks including same, and methods for making same XEROX CORP 2016-06-01 CN disclosed
CN-102533002-B Solid ink containing ketone wax and side chain acid amides Xerox Corp. (US) Patent Dept. 020 Xerox Square 100 Clinton Avenue Rochester New (US) 2016-01-27 CN disclosed
CN-104893408-A Solid phase change fluorescent ink, ink sets and method for forming image XEROX CORP 2015-09-09 CN disclosed
CN-101684215-B Solid phase change fluorescent inks, ink sets and methods of forming images XEROX CORP. (US) 2015-08-05 CN disclosed
CN-102086322-B Comprise the solid ink of the polyhydroxyalkanoatefrom compound for strengthening the property Xerox Corp. (US) Patent Dept. 020 Xerox Square 100 Clinton Avenue Rochester New (US) 2015-07-29 CN disclosed
CN-102134201-B Low molecular weight pigment dispersants for phase change ink XEROX CORP 2015-07-08 CN disclosed
CN-101891654-B Low molecular weight quaternary ammonium salt dispersants XEROX CORP 2015-04-29 CN disclosed
CN-101891654-A Low molecular weight quaternary ammonium salt dispersants XEROX CORP 2010-11-24 CN disclosed
CN-101891985-A The pigmented phase change ink that contains low molecular weight quaternary ammonium salt dispersants XEROX CORP 2010-11-24 CN disclosed
CN-101805537-A Ink-jet ink containing nanodiamond black coloring agent XEROX CORP 2010-08-18 CN disclosed
CN-101735685-A Phase change inks containing graphene-based carbon allotrope colorants, water-based ink and using method thereof XEROX CORP 2010-06-16 CN disclosed
CN-101684216-A Ink carriers containing low viscosity functionalized waxes, phase change inks including same, and methods for making same XEROX CORP 2010-03-31 CN disclosed
CN-101684215-A Solid phase change fluorescent inks, ink sets and methods of forming images XEROX CORP 2010-03-31 CN disclosed
CN-101643603-A Ink vehicles containing surface-modified nanoparticles and phase change inks including the same XEROX CORP 2010-02-10 CN disclosed
US-7595347-B2 Method for protecting normal cells from cytotoxicity of chemotherapeutic agents Temple University—Of the Commonwealth System of Higher Education (US) 2009-09-29 US disclosed
US-7579587-B2 Thermally assisted membrane introduction mass spectrometry (MIMS) interface and method of use thereof VANCOUVER ISLAND UNIVERSITY (CA) 2009-08-25 US disclosed
US-20070181799-A1 THERMALLY ASSISTED MEMBRANE INTRODUCTION MASS SPECTROMETRY (MIMS) INTERFACE AND METHOD OF USE THEREOF MALASPINA UNIVERSITY-COLLEGE (CA) 2007-08-09 US disclosed