Sugi Predict

Sugi Predict / Compounds / SCHEMBL4589500

SCHEMBL4589500

SCHEMBL4589500

O=S(=O)(O)C(Cl)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SRC P12931 3/20 0.54
▸ ALDH1A1 P00352 2/20 0.52
▸ TSHR P16473 2/20 0.46
▸ SMN1; SMN2 Q16637 1/20 0.42
▸ LMNA P02545 3/20 0.41
▸ KDM4E B2RXH2 1/20 0.41
▸ GMNN O75496 1/20 0.41
▸ POLB P06746 1/20 0.41
▸ MAPT P10636 1/20 0.41
▸ HPGD P15428 1/20 0.41
▸ PMP22 Q01453 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ NPSR1 Q6W5P4 1/20 0.41
▸ TDP1 Q9NUW8 1/20 0.41
▸ CYP2D6 P10635 1/20 0.41
▸ CYP2C19 P33261 1/20 0.41
▸ CA12 O43570 1/20 0.40
▸ CA1 P00915 1/20 0.40
▸ CA2 P00918 1/20 0.40
▸ CA9 Q16790 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3852183 0.80 TSHR (0.50) SRCALDH1A1TSHRLMNATDP1
SCHEMBL8347652 0.79 ACP3 (0.47) SRCALDH1A1TSHRLMNAMAPT
SCHEMBL1095271 0.78 TSHR (0.48) SRCALDH1A1TSHRLMNATDP1
SCHEMBL3616092 0.77 CYP1A2 (0.39) SRCCYP2C19CA12CA1CA2
SCHEMBL5200608 0.76 TSHR (0.46) SRCALDH1A1TSHRLMNAKDM4E
SCHEMBL5200599 0.76 TSHR (0.46) SRCALDH1A1TSHRLMNATDP1
SCHEMBL4440349 0.76 TSHR (0.46) SRCALDH1A1TSHRCA12CA1
SCHEMBL496890 0.75 SRC (0.58) SRCALDH1A1TSHRSMN1; SMN2LMNA
SCHEMBL153281 0.75 SRC (0.58) SRCALDH1A1TSHRSMN1; SMN2LMNA
Hydrochloric Acid SCHEMBL251517 0.73 SRC (0.56) SRCALDH1A1TSHRSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 318 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250084085-A1 PROCESS OF MAKING 2-[(3R)-2-[4-AMINO-3-(2-FLUORO-4-PHENOXY-PHENYL)PYRAZOLO[3,4-D]PYRIMIDIN-1-YL]PIPERIDINE-1-CARBONYL]-4-METHYL-4[4-(OXETAN-3-YL)PIPERAZIN-1-YL]-PENT-2-ENENITRILE AND SOLVATE FORMS THEREOF PRINCIPIA BIOPHARMA INC. (US) 2025-03-13 — — US claimed
WO-2025029842-A2 PROCESS OF MAKING 2-[(3R)-2-[4-AMINO-3-(2-FLUORO-4-PHENOXY- PHENYL)PYRAZOLO[3,4-D]PYRIMIDIN-L-YL]PIPERIDINE-L-CARBONYL]-4- METHYL-4[4-(OXETAN-3-YL)PIPERAZIN-L-YL]-PENT-2-ENENITRILE AND SOLVATE FORMS THEREOF PRINCIPIA BIOPHARMA INC. (US) 2025-02-06 — — WO claimed
CN-115246757-B Preparation method of aryl acetamide compound 浙江理工大学 2023-10-20 — — CN claimed
CN-115246757-A Preparation method of aryl acetamide compound 浙江理工大学 2022-10-28 — — CN claimed
CN-111183214-B Leuco colorants as bluing agents in laundry care compositions 宝洁公司 2022-06-14 — — CN claimed
CN-110903480-B Preparation method of controllable molecular weight polysulfone 万华化学集团股份有限公司 2022-04-22 — — CN claimed
US-11299634-B2 Reactive leuco compounds and compositions comprising the same MILLIKEN & COMPANY (US) 2022-04-12 — — US claimed
US-20220089974-A1 LAUNDRY CARE COMPOSITIONS AND METHODS FOR DETERMINING THEIR AGE PROCTER & GAMBLE (US) 2022-03-24 — — US claimed
CN-111183215-B Laundry care compositions and methods for determining their age 宝洁公司 2022-03-15 — — CN claimed
US-11230686-B2 Laundry care compositions and methods for determining their age THE PROCTER & GAMBLE COMPANY (US) 2022-01-25 — — US claimed
CN-109233322-A A kind of Vickery blue and preparation method thereof 绍兴金美珂化工有限公司 2019-01-18 — — CN claimed
US-20180148672-A1 LEUCO COLORANTS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS MILLIKEN & COMPANY 2018-05-31 — — US claimed
US-20180119068-A1 METHODS OF USING LEUCO COLORANTS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2018-05-03 — — US claimed
US-20180118942-A1 REACTIVE LEUCO COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME MILLIKEN & COMPANY 2018-05-03 — — US claimed
US-20180119067-A1 LEUCO COLORANTS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2018-05-03 — — US claimed
US-20180119057-A1 METHODS OF USING LEUCO COLORANTS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2018-05-03 — — US claimed
EP-1928853-A2 PROCESS FOR PRODUCTION OF DELTA-9-TETRAHYDROCANNABINOL AMR Technology, Inc. (US) 2008-06-11 — — EP claimed
WO-2007041167-A2 PROCESS FOR PRODUCTION OF DELTA-9-TETRAHYDROCANNABINOL AMR TECHNOLOGY, INC. (US) 2007-04-12 — — WO claimed
US-4267319-A CATIONIC DYES AND N-HETEROCYCLIC CATIONIC POLYMERS; PRINTING PAPER; ORANGE OR RED BASF AKTIENGESELLSCHAFT (DE) 1981-05-12 — — US claimed
US-4131619-A Preparation of 2-chloro-4-toluenesulfonyl chloride THE DOW CHEMICAL COMPANY (US) 1978-12-26 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250084085-A1 PROCESS OF MAKING 2-[(3R)-2-[4-AMINO-3-(2-FLUORO-4-PHENOXY-PHENYL)PYRAZOLO[3,4-D]PYRIMIDIN-1-YL]PIPERIDINE-1-CARBONYL]-4-METHYL-4[4-(OXETAN-3-YL)PIPERAZIN-1-YL]-PENT-2-ENENITRILE AND SOLVATE FORMS THEREOF EPB41, HTR4, HTR3C SRC 3464/4885ALDH1A1 831/4885TSHR 2828/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.