Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2577166 | 0.97 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL16667448 | 0.93 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL3417371 | 0.93 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL1643136 | 0.93 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL2343557 | 0.93 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL8901734 | 0.92 | TSHR (0.45) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL340848 | 0.91 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL16223507 | 0.91 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL16223361 | 0.91 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL16223419 | 0.91 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125834-A1 | METHOD FOR THE PRODUCTION OF POLYMERISABLE SILICONES | Wacker Chemie AG (DE) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008090013-A1 | METHOD FOR THE PRODUCTION OF POLYMERISABLE SILICONES | WACKER CHEMIE AG (DE) | 2008-07-31 | — | — | WO | disclosed |