Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 6/20 | 0.32 |
| ▸ | DGKA | P23743 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4440431 | 0.93 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL2577166 | 0.93 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL1643136 | 0.89 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL3417371 | 0.89 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL8901734 | 0.88 | TSHR (0.45) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5481563 | 0.88 | TSHR (0.43) | TSHRTHRBLMNAPOLBAPEX1 | |
| SCHEMBL340955 | 0.87 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL3192863 | 0.87 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL16223361 | 0.87 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL340848 | 0.87 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1628916-B1 | PYROGENICALLY PREPARED, SURFACE MODIFIED ALUMINUM OXIDE | EVONIK DEGUSSA GMBH (DE) | 2015-04-29 | — | — | EP | claimed |