Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | LAP3 | P28838 | 1/20 | 0.31 |
| ▸ | MVD | P53602 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4437316 | 0.76 | TP53 (0.35) | TP53 | |
| SCHEMBL9506705 | 0.74 | TP53 (0.33) | TP53 | |
| SCHEMBL14890392 | 0.72 | TP53 (0.40) | ADAMTS4SLC7A5TP53 | |
| SCHEMBL15023 | 0.72 | TP53 (0.40) | ADAMTS4SLC7A5TP53 | |
| SCHEMBL18921013 | 0.72 | TP53 (0.40) | ADAMTS4SLC7A5TP53 | |
| SCHEMBL214942 | 0.72 | TP53 (0.40) | ADAMTS4SLC7A5TP53 | |
| SCHEMBL2981557 | 0.71 | FDPS (0.37) | LAP3 | |
| SCHEMBL2981558 | 0.71 | FDPS (0.37) | LAP3 | |
| SCHEMBL4300140 | 0.70 | SLC7A5 (0.43) | ADAMTS4SLC7A5TP53 | |
| SCHEMBL10654070 | 0.70 | SLC7A5 (0.43) | ADAMTS4SLC7A5TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4391747-B2 | — | — | 2009-12-24 | — | — | JP | claimed |
| EP-1385379-B1 | INSECTICIDE AND METHOD OF CONTROLLING INSECTS | NUFARM AUSTRALIA LTD (AU) | 2008-08-06 | — | — | EP | claimed |
| US-7217831-B2 | Insecticide and method of controlling insects | NUFARM - AUSTRALIA LIMITED (AU) | 2007-05-15 | — | — | US | claimed |
| JP-2004532837-A | — | — | 2004-10-28 | — | — | JP | claimed |
| US-20040176424-A1 | Insecticide and method of controlling insects | NUFARM AUSTRALIA LIMITED (AU) | 2004-09-09 | — | — | US | claimed |
| EP-1385379-A4 | INSECTICIDE AND METHOD OF CONTROLLING INSECTS | NUFARM AUSTRALIA LTD (AU) | 2004-06-23 | — | — | EP | claimed |
| EP-1385379-A1 | INSECTICIDE AND METHOD OF CONTROLLING INSECTS | NUFARM AUSTRALIA LIMITED (AU) | 2004-02-04 | — | — | EP | claimed |
| WO-2002078448-A1 | INSECTICIDE AND METHOD OF CONTROLLING INSECTS | NUFARM AUSTRALIA LIMITED (AU) | 2002-10-10 | — | — | WO | claimed |
| EP-1385379-B1 | INSECTICIDE AND METHOD OF CONTROLLING INSECTS | NUFARM AUSTRALIA LTD (AU) | 2008-08-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176424-A1 | Insecticide and method of controlling insects | DDT, CYP2B6, NR4A1 | ADAMTS4 3915/4885SLC7A5 1348/4885TP53 4859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.