SCHEMBL444193

SCHEMBL444193

C=C(C)C(=O)C=C(C)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.35
PTGS1 P23219 1/20 0.33
AKR1C3 P42330 1/20 0.33
CYP2C9 P11712 1/20 0.33
PARP1 P09874 1/20 0.32
PARP15 Q460N3 1/20 0.32
PARP10 Q53GL7 1/20 0.32
MAPT P10636 1/20 0.32
ALDH1A1 P00352 2/20 0.31
CYP1A2 P05177 1/20 0.30
FFAR3 O14843 1/20 0.30
LCK P06239 1/20 0.30
FYN P06241 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL8425141 0.97 TDP1 (0.33) TDP1PTGS1AKR1C3CYP2C9PARP1
SCHEMBL9721158 0.97 TDP1 (0.33) TDP1PTGS1AKR1C3CYP2C9PARP1
Methacrylic Acid SCHEMBL8425146 0.97 TDP1 (0.33) TDP1PTGS1AKR1C3CYP2C9PARP1
SCHEMBL27734787 0.84 PTGS1 (0.33) PTGS1AKR1C3CYP2C9MAPTALDH1A1
Acrylic Acid SCHEMBL8426417 0.84 LMNA (0.37) TDP1ALDH1A1
Acrylic Acid SCHEMBL8426413 0.84 LMNA (0.37) TDP1ALDH1A1
SCHEMBL16653704 0.80 CYP1A2 (0.38) PTGS1AKR1C3CYP2C9PARP1PARP15
SCHEMBL1300006 0.80 CYP1A2 (0.38) PTGS1AKR1C3CYP2C9PARP1PARP15
SCHEMBL16653701 0.80 CYP1A2 (0.38) PTGS1AKR1C3CYP2C9PARP1PARP15
Methacrylic Acid SCHEMBL1443532 0.79 HTT (0.39) TDP1PTGS1AKR1C3CYP2C9MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4706759-A2 PHARMACEUTICAL COMPOSITIONS CONTAINING ENTEROKINE-RELEASING SUBSTANCES IN MULTIPLE DOSAGE FORMS IN COMBINATION WITH GELLING AGENTS Aphaia Pharma AG (CH) 2026-03-11 EP claimed
WO-2025119939-A1 TREATMENT OF OBESITY AND RELATED CONDITIONS BY CIRCADIAN ADMINISTRATION OF ENTEROKINE-STIMULATING COMPOSITIONS APHAIA PHARMA AG (CH) 2025-06-12 WO claimed
EP-4164592-B1 PHARMACEUTICAL COMPOSITIONS CONTAINING ENTEROKINE-RELEASING SUBSTANCES IN MULTIPLE DOSAGE FORMS IN COMBINATION WITH GELLING AGENTS APHAIA IP AG (CH) 2025-05-07 EP claimed
US-20240116037-A1 SCRF COATINGS JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2024-04-11 US claimed
WO-2024074802-A1 SCRF COATINGS JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2024-04-11 WO claimed
EP-4349458-A1 SCRF COATINGS Johnson Matthey Public Limited Company (GB) 2024-04-10 EP claimed
US-20230233471-A1 Pharmaceutical Compositions Containing Enterokine Releasing Substances In Multiple Dosage Forms In Combination With Gelling Agents APHAIA PHARMA AG (CH) 2023-07-27 US claimed
EP-3681922-B1 RADIATION CURABLE AQUEOUS COMPOSITIONS ALLNEX Belgium SA (BE) 2022-12-07 EP claimed
US-20220331256-A1 PHARMACEUTICAL ORAL DOSAGE FORMS FOR TREATMENT OF METABOLIC DISORDERS AND RELATED DISEASES THROUGH ORCHESTRATED RELEASE OF ENTEROKINES APHAIA PHARMA AG (CH) 2022-10-20 US claimed
EP-3666262-B1 PHARMACEUTICAL ORAL DOSAGE FORMS FOR TREATMENT OF METABOLIC DISORDERS AND RELATED DISEASES THROUGH ORCHESTRATED RELEASE OF ENTEROKINES APHAIA IP AG (CH) 2021-11-10 EP claimed
WO-2020120518-A1 PHARMACEUTICAL ORAL DOSAGE FORMS FOR TREATMENT OF METABOLIC DISORDERS AND RELATED DISEASES THROUGH ORCHESTRATED RELEASE OF ENTEROKINES APHAIA PHARMA AG (CH) 2020-06-18 WO claimed
WO-2020120519-A1 COMBINATORIAL ORAL TREATMENT OF METABOLIC DISORDERS THROUGH ORCHESTRATED RELEASE OF ENTEROKINES APHAIA PHARMA AG (CH) 2020-06-18 WO claimed
EP-3666262-A1 PHARMACEUTICAL ORAL DOSAGE FORMS FOR TREATMENT OF METABOLIC DISORDERS AND RELATED DISEASES THROUGH ORCHESTRATED RELEASE OF ENTEROKINES Aphaia Pharma AG (CH) 2020-06-17 EP claimed
CN-101381438-B Compound material constructed by molecular engram and fluorescent conjugated polymer, preparation and application TONGCHUANG HAICHENG SCIENCE TECHNOLOGY DEV BEIJING CO LTD 2013-06-26 CN claimed
EP-1377369-B1 SUBSTRATES, PREPARATION AND USE CYTEC SURFACE SPECIALTIES SA (BE) 2011-05-11 EP claimed
CN-101381438-A Compound material constructed by molecular engram and fluorescent conjugated polymer, preparation and application SHANGHAI INST MICROSYS & INF (CN) 2009-03-11 CN claimed
EP-0747455-B1 Friction coating for film backings NORTON CO (US) 1999-07-21 EP claimed
US-20260071218-A1 Oral Delivery of Antisense Conjugates Targeting PCSK9 CIVI BIOPHARMA INC (US) 2026-03-12 US disclosed
US-4267265-A PLASTICIZER AND AN ORGANIC FLUORINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1981-05-12 US disclosed
US-4078004-A OXIDATION OF ISOBUTYLENE, METAL OXIDE CATALYST, EXPANDED PERLITE SUPPORT ROHM AND HAAS COMPANY (US) 1978-03-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260071218-A1 Oral Delivery of Antisense Conjugates Targeting PCSK9 PCSK9, ALPI, SLC10A2 TDP1 2676/4885PTGS1 4700/4885AKR1C3 853/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.