Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL444045 | 0.76 | MEN1 (0.32) | MEN1ALDH1A1MAPTMAPK1KMT2A | |
| SCHEMBL15159478 | 0.72 | — | — | |
| SCHEMBL1514351 | 0.72 | — | — | |
| SCHEMBL12976271 | 0.68 | NPC1 (0.51) | MEN1ALDH1A1KMT2AHTTL3MBTL1 | |
| SCHEMBL13176356 | 0.68 | — | — | |
| SCHEMBL18923146 | 0.68 | — | — | |
| SCHEMBL13019678 | 0.68 | ALDH1A1 (0.47) | MEN1ALDH1A1MAPTMAPK1KMT2A | |
| SCHEMBL11764899 | 0.68 | — | — | |
| SCHEMBL23084787 | 0.63 | MEN1 (0.55) | MEN1ALDH1A1MAPTMAPK1KMT2A | |
| SCHEMBL21720402 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8470739-B2 | Isothiazolyloxyphenylamidines and their use as fungicides | BAYER CROPSCIENE AG (DE) | 2013-06-25 | — | — | US | disclosed |
| US-8470739-B2 | Isothiazolyloxyphenylamidines and their use as fungicides | BAYER CROPSCIENE AG (DE) | 2013-06-25 | — | — | US | disclosed |
| US-8470739-B2 | Isothiazolyloxyphenylamidines and their use as fungicides | BAYER CROPSCIENE AG (DE) | 2013-06-25 | — | — | US | disclosed |
| US-8138211-B2 | Isothiazolyloxyphenylamidines and their use as fungicides | BAYER CROPSCIENCE AG (DE) | 2012-03-20 | — | — | US | disclosed |
| US-8138211-B2 | Isothiazolyloxyphenylamidines and their use as fungicides | BAYER CROPSCIENCE AG (DE) | 2012-03-20 | — | — | US | disclosed |
| US-8138211-B2 | Isothiazolyloxyphenylamidines and their use as fungicides | BAYER CROPSCIENCE AG (DE) | 2012-03-20 | — | — | US | disclosed |
| US-20120065061-A1 | ISOTHIAZOLYLOXYPHENYLAMIDINES AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2012-03-15 | — | — | US | disclosed |
| US-20120065061-A1 | ISOTHIAZOLYLOXYPHENYLAMIDINES AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2012-03-15 | — | — | US | disclosed |
| US-20120065061-A1 | ISOTHIAZOLYLOXYPHENYLAMIDINES AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2012-03-15 | — | — | US | disclosed |
| EP-2391612-A1 | Isothiazolyloxyphenyl amidines and use thereof as fungicides | Bayer CropScience AG (DE) | 2011-12-07 | — | — | EP | disclosed |
| US-20110130282-A1 | Isothiazolyloxyphenylamidines and their use as fungicides | BAYER CROPSCIENCE AG (DE) | 2011-06-02 | — | — | US | disclosed |
| US-20110130282-A1 | Isothiazolyloxyphenylamidines and their use as fungicides | BAYER CROPSCIENCE AG (DE) | 2011-06-02 | — | — | US | disclosed |
| US-20110130282-A1 | Isothiazolyloxyphenylamidines and their use as fungicides | BAYER CROPSCIENCE AG (DE) | 2011-06-02 | — | — | US | disclosed |
| EP-2223917-A1 | Isothiazolyloxyphenylamidines and their use as fungicides | Bayer CropScience AG (DE) | 2010-09-01 | — | — | EP | disclosed |
| WO-2010086118-A1 | ISOTHIAZOLYLOXYPHENYL AMIDINES AND USE THEREOF AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2010-08-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065061-A1 | ISOTHIAZOLYLOXYPHENYLAMIDINES AND THEIR USE AS FUNGICIDES | DDT, CYP3A5, INMT | MEN1 784/4885ALDH1A1 526/4885MAPT 3061/4885 |
| US-20110130282-A1 | Isothiazolyloxyphenylamidines and their use as fungicides | DDT, CYP3A5, INMT | MEN1 784/4885ALDH1A1 526/4885MAPT 3061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.