SCHEMBL444270

SCHEMBL444270

C[CH]OC(=O)OCCCC

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.54
ALDH1A1 P00352 1/20 0.52
TSHR P16473 5/20 0.50
HPGD P15428 1/20 0.50
HCAR2 Q8TDS4 3/20 0.47
NAAA Q02083 1/20 0.42
ESR1 P03372 2/20 0.42
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MAPT P10636 1/20 0.41
RAB9A P51151 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
EPHX1 P07099 1/20 0.39
LMNA P02545 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
MAPK1 P28482 1/20 0.39
CYP2C19 P33261 1/20 0.39
NR1H2 P55055 1/20 0.39
RNASEL Q05823 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL450736 0.94 NAAA (0.50) ATMALDH1A1TSHRHPGDHCAR2
SCHEMBL5510321 0.92 NAAA (0.53) ATMALDH1A1TSHRHCAR2NAAA
SCHEMBL5517476 0.92 NAAA (0.53) ATMALDH1A1TSHRHCAR2NAAA
SCHEMBL5512033 0.92 NAAA (0.53) ATMALDH1A1TSHRHCAR2NAAA
SCHEMBL5512249 0.92 NAAA (0.53) ATMALDH1A1TSHRHCAR2NAAA
SCHEMBL450585 0.92 NAAA (0.53) ATMALDH1A1TSHRHCAR2NAAA
SCHEMBL5507449 0.92 NAAA (0.53) ATMALDH1A1TSHRHCAR2NAAA
SCHEMBL5506856 0.92 NAAA (0.53) ATMALDH1A1TSHRHCAR2NAAA
SCHEMBL5514096 0.92 NAAA (0.53) ATMALDH1A1TSHRHCAR2NAAA
SCHEMBL9299181 0.88 ATM (0.42) ATMALDH1A1TSHRHPGDHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 698 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2189443-B1 TRICYCLIC AMIDE COMPOUND RES FOUND ITSUU LAB (JP) 2013-10-23 EP claimed
US-5616600-A Griseolic acid compounds and their use as a phosphodiesterase inhibitor SANKYO COMPANY, LIMITED (JP) 1997-04-01 US claimed
US-5491167-A INHIBITORS OF CHOLESTEROL BIOSYNTHESIS SANKYO COMPANY, LIMITED (JP) 1996-02-13 US claimed
US-5480987-A 2-substituted alkyl-3-carboxy carbapenems as antibiotics and a method of producing them AMERICAN CYANAMID COMPANY (US) 1996-01-02 US claimed
EP-0643059-A1 3-(3-Pyridinyl)-1H-indoles as thromboxane A2 synthetase inhibitors Pfizer Limited (GB) 1995-03-15 EP claimed
US-5369102-A B-lactamase inhibitors AMERICAN CYANAMID COMPANY (US) 1994-11-29 US claimed
EP-0594588-A1 CYCLOALKYL-SUBSTITUTED GLUTARAMIDE ANTIHYPERTENSIVE AGENTS Pfizer Limited (GB) 1994-05-04 EP claimed
EP-0358398-B1 CYCLOALKYL-SUBSTITUTED GLUTARAMIDE ANTIHYPERTENSIVE AGENTS Pfizer Limited (GB) 1993-03-10 EP claimed
EP-0478874-A2 Novel 2-substituted alkyl-3-carboxy carbapenems as antibiotics and a method of producing them AMERICAN CYANAMID COMPANY (US) 1992-04-08 EP claimed
US-5068232-A Bactericides AMERICAN CYANAMID COMPANY (US) 1991-11-26 US claimed
WO-1991013054-A1 CYCLOALKYL-SUBSTITUTED GLUTARAMIDE ANTIHYPERTENSIVE AGENTS PFIZER LIMITED (GB) 1991-09-05 WO claimed
US-4975444-A INHIBITORS OF ANGIORENSIN-CONVERTING ENZYME AS WELL AS A ENDOPEPTIDASE; CARDIOTONIC AGENTS; GLAUCOMA; DIURETICS PFIZER INC. (US) 1990-12-04 US claimed
EP-0370454-A2 Renin-inhibiting amino diol derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1990-05-30 EP claimed
EP-0358398-A1 Cycloalkyl-substituted glutaramide antihypertensive agents Pfizer Limited (GB) 1990-03-14 EP claimed
EP-0335390-A2 Novel cephalosporin compounds SAGAMI CHEMICAL RESEARCH CENTER (JP) 1989-10-04 EP claimed
EP-0329013-A2 Renin-inhibiting amino acid derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1989-08-23 EP claimed
US-4376770-A OXACEPHALOSPORINS SHIONOGI & CO., LTD. (JP) 1983-03-15 US claimed
US-20240131180-A1 DRUG ANTIBODY CONJUGATES PHARMA MAR, S.A. (ES) 2024-04-25 US disclosed
EP-0008917-A1 Penam-3-carboxylic acid 1,1-dioxides, process for their preparation and pharmaceutical compositions PFIZER INC. (US) 1980-03-19 EP disclosed
US-4180503-A FOR DYEING POLYAMIDES BAYER AKTIENGESELLSCHAFT (DE) 1979-12-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240131180-A1 DRUG ANTIBODY CONJUGATES STT3B, STT3A, TTL ATM 3058/4885ALDH1A1 785/4885TSHR 1530/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.