Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 3/20 | 0.37 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2308582 | 0.81 | CA12 (0.38) | CA12CA1CA2CA9ACE | |
| SCHEMBL1950731 | 0.78 | ACE (0.50) | ACEREN | |
| SCHEMBL6478173 | 0.78 | ACE (0.50) | ACEREN | |
| SCHEMBL258790 | 0.78 | ACE (0.50) | ACEREN | |
| SCHEMBL5642161 | 0.76 | ACE (0.39) | ACEREN | |
| SCHEMBL27957044 | 0.76 | ACE (0.49) | ACE | |
| SCHEMBL21874335 | 0.76 | ACE (0.49) | ACE | |
| SCHEMBL3791081 | 0.76 | ACE (0.49) | ACE | |
| SCHEMBL27579442 | 0.76 | NPSR1 (0.40) | — | |
| SCHEMBL25305712 | 0.76 | ACE (0.41) | ACEREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090036435-A1 | Pharmaceutical Compounds | ASTEX THERAPEUTICS LIMITED (UK) | 2009-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036435-A1 | Pharmaceutical Compounds | CDK9, CDK4, CDK19 | CA12 659/4885CA1 468/4885CA2 528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.