Benzidine

Benzidine

SCHEMBL4442914

Nc1ccc(-c2ccc(N)c(O)c2)cc1O.Nc1ccc(-c2ccc(N)cc2)cc1

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.81
HSD17B10 Q99714 4/20 0.81
ALOX15 P16050 3/20 0.81
ALDH1A1 P00352 4/20 0.52
TDP1 Q9NUW8 4/20 0.52
TP53 P04637 1/20 0.52
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
KDM4E B2RXH2 2/20 0.48
GAA P10253 2/20 0.48
MAPT P10636 2/20 0.48
USP2 O75604 1/20 0.48
LMNA P02545 1/20 0.48
HSP90AA1 P07900 1/20 0.48
HPGD P15428 1/20 0.48
ALOX12 P18054 1/20 0.48
HTT P42858 1/20 0.48
ESR2 Q92731 1/20 0.47
POLB P06746 1/20 0.46
RAB9A P51151 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL564452 1.00 CYP3A4 (0.81) CYP3A4HSD17B10ALOX15ALDH1A1TDP1
Benzidine SCHEMBL6430439 1.00 CYP3A4 (0.81) CYP3A4HSD17B10ALOX15ALDH1A1TDP1
SCHEMBL30313807 0.93 ALOX15 (0.94) CYP3A4HSD17B10ALOX15ALDH1A1TDP1
SCHEMBL20945278 0.93 ALOX15 (0.94) CYP3A4HSD17B10ALOX15ALDH1A1TDP1
SCHEMBL23924225 0.90 CYP3A4 (1.00) CYP3A4HSD17B10ALOX15ALDH1A1TDP1
SCHEMBL29365557 0.90 CYP3A4 (1.00) CYP3A4HSD17B10ALOX15ALDH1A1TDP1
SCHEMBL29549758 0.90 CYP3A4 (1.00) CYP3A4HSD17B10ALOX15ALDH1A1TDP1
SCHEMBL105866 0.90 CYP3A4 (1.00) CYP3A4HSD17B10ALOX15ALDH1A1TDP1
Water SCHEMBL7721550 0.87 CYP3A4 (0.94) CYP3A4HSD17B10ALOX15ALDH1A1TDP1
Ammonia Solution, Strong SCHEMBL6653834 0.87 CYP3A4 (0.94) CYP3A4HSD17B10ALOX15ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2051796-A1 METHOD OF MEMBRANE SEPARATION OF AN OLEFIN CONTAINED IN A MIXTURE OF HYDROCARBONS IFP (FR) 2009-04-29 EP disclosed
WO-2008017743-A1 METHOD OF MEMBRANE SEPARATION OF AN OLEFIN CONTAINED IN A MIXTURE OF HYDROCARBONS IFP (FR) 2008-02-14 WO disclosed
EP-0544165-B1 Phenylquinoxaline copolymers SIEMENS AG (DE) 1996-06-05 EP disclosed
EP-0544165-A1 Phenylquinoxaline copolymers SIEMENS AKTIENGESELLSCHAFT (DE) 1993-06-02 EP disclosed