Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.65 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.65 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.65 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.65 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.65 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.65 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6591360 | 0.98 | TDP1 (0.68) | TDP1L3MBTL1LMNAMAPTHDAC8 | |
| SCHEMBL5214695 | 0.93 | TDP1 (0.64) | TDP1L3MBTL1LMNAMAPTHDAC8 | |
| Hydrochloric Acid SCHEMBL27261595 | 0.91 | TDP1 (0.62) | TDP1L3MBTL1LMNAMAPTHDAC8 | |
| SCHEMBL12612568 | 0.87 | TDP1 (0.53) | TDP1L3MBTL1LMNAMAPTHDAC8 | |
| SCHEMBL8599281 | 0.85 | TDP1 (0.77) | TDP1L3MBTL1LMNAMAPTHDAC8 | |
| SCHEMBL1697056 | 0.85 | MAPT (0.57) | TDP1L3MBTL1LMNAMAPTHDAC8 | |
| SCHEMBL27516050 | 0.84 | TDP1 (1.00) | TDP1L3MBTL1LMNAMAPTHDAC8 | |
| SCHEMBL9057671 | 0.84 | TDP1 (1.00) | TDP1L3MBTL1LMNAMAPTHDAC8 | |
| SCHEMBL8519287 | 0.84 | TDP1 (1.00) | TDP1L3MBTL1LMNAMAPTHDAC8 | |
| SCHEMBL669665 | 0.84 | GAA (0.56) | TDP1L3MBTL1LMNAMAPTHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275581-A1 | RENIN INHIBITORS | VITAE PHARMACEUTICALS, INC. | 2009-11-05 | — | — | US | disclosed |
| US-20090264428-A1 | Renin Inhibitors | VITAE PHARMACEUTICALS, INC. | 2009-10-22 | — | — | US | disclosed |
| EP-0934773-B1 | Microcapsule having a specific wall and method for producing the same | SEIWA KASEI CO LTD (JP) | 2004-02-04 | — | — | EP | disclosed |
| US-6337089-B1 | FOR USE IN COSMETICS | SEIWA KASEI COMPANY, LIMITED (JP) | 2002-01-08 | — | — | US | disclosed |
| EP-0934773-A2 | Microcapsule having a specific wall and method for producing the same | SEIWA KASEI CO., LTD. (JP) | 1999-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275581-A1 | RENIN INHIBITORS | REN, ACE, SERPINB1 | TDP1 1834/4885L3MBTL1 4439/4885LMNA 3150/4885 |
| US-20090264428-A1 | Renin Inhibitors | REN, ACE, SERPINB1 | TDP1 1382/4885L3MBTL1 3320/4885LMNA 2089/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.