SCHEMBL4443402

SCHEMBL4443402

C=C(C)C(=O)Oc1cc(C)c(O)c(-n2nc3ccccc3n2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 10/20 0.46
RAB9A P51151 10/20 0.46
SMN1; SMN2 Q16637 6/20 0.46
ALDH1A1 P00352 5/20 0.46
POLB P06746 3/20 0.43
IGF2BP2 Q9Y6M1 1/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 6/20 0.40
HPGD P15428 4/20 0.40
KDM4E B2RXH2 4/20 0.40
TDP1 Q9NUW8 2/20 0.40
ELANE P08246 1/20 0.40
NPSR1 Q6W5P4 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
PPARG P37231 1/20 0.37
PPARA Q07869 1/20 0.37
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
USP2 O75604 1/20 0.36
ATM Q13315 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2777176 0.85 NPC1 (0.41) NPC1RAB9ASMN1; SMN2ALDH1A1POLB
SCHEMBL2780353 0.84 NPC1 (0.45) NPC1RAB9ASMN1; SMN2ALDH1A1POLB
SCHEMBL29384504 0.82 NPC1 (0.52) NPC1RAB9ASMN1; SMN2ALDH1A1POLB
SCHEMBL93326 0.82 NPC1 (0.52) NPC1RAB9ASMN1; SMN2ALDH1A1POLB
SCHEMBL4444701 0.81 NPC1 (0.56) NPC1RAB9ASMN1; SMN2ALDH1A1POLB
SCHEMBL4665991 0.81 NPC1 (0.38) NPC1RAB9ASMN1; SMN2ALDH1A1POLB
SCHEMBL27584413 0.81 NPC1 (0.38) NPC1RAB9ASMN1; SMN2ALDH1A1POLB
SCHEMBL4441549 0.80 IGF2BP2 (0.39) NPC1RAB9ASMN1; SMN2ALDH1A1POLB
SCHEMBL29382372 0.80 NPC1 (0.45) NPC1RAB9ASMN1; SMN2ALDH1A1POLB
SCHEMBL4444924 0.80 NPC1 (0.45) NPC1RAB9ASMN1; SMN2ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160054840-A1 TOUCH SENSOR WITH FRONT PANEL ASAHI GLASS COMPANY, LIMITED (JP) 2016-02-25 US disclosed
US-20130164543-A1 FRONT PANEL FOR TOUCH SENSOR ASAHI GLASS COMPANY, LIMITED (JP) 2013-06-27 US disclosed
EP-1256611-B1 Aqueous dispersion and coated product JSR CORP (JP) 2009-07-29 EP disclosed
US-6726997-B2 WWATERPROOF, HARDNESS, RATION TRANSPARENT; PROTECTIVE COATINGS JSR CORPORATION (JP) 2004-04-27 US disclosed
EP-0899091-B1 Transparent coated molded product and method for producing the same ASAHI GLASS CO LTD (JP) 2003-10-29 EP disclosed
US-20030073779-A1 Aqueous dispersion and coated product JSR CORPORATION (JP) 2003-04-17 US disclosed
EP-1256611-A2 Aqueous dispersion and coated product JSR Corporation (JP) 2002-11-13 EP disclosed
US-6383641-B1 CURED INTERIOR LAYER FROM POLYFUNCTIONAL COMPOUND; EXTERIOR SILICA COATING CURED FROM POLYSILAZANE; WEAR RESISTANCE, WEATHERPROOF ASAHI GLASS COMPANY LTD. (JP) 2002-05-07 US disclosed
EP-0899091-A2 Transparent coated molded product and method for producing the same Asahi Glass Company Ltd. (JP) 1999-03-03 EP disclosed