Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA9 | Q16790 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 7/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.39 |
| ▸ | PLG | P00747 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | KLK1 | P06870 | 1/20 | 0.39 |
| ▸ | KLK6 | Q92876 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13501533 | 1.00 | CA12 (0.46) | CA12CA1CA2CA9HTT | |
| SCHEMBL13501538 | 1.00 | CA12 (0.46) | CA12CA1CA2CA9HTT | |
| SCHEMBL4829862 | 0.85 | CA12 (0.48) | CA12CA1CA2CA9HTT | |
| SCHEMBL28511516 | 0.84 | AURKA (0.48) | CA12CA1CA2CA9HTT | |
| SCHEMBL30713077 | 0.84 | AURKA (0.48) | CA12CA1CA2CA9HTT | |
| Hydrochloric Acid SCHEMBL4826620 | 0.84 | CA12 (0.47) | CA12CA1CA2CA9HTT | |
| SCHEMBL8169368 | 0.83 | LOXL2 (0.38) | CA12CA1CA2CA9HTT | |
| SCHEMBL10955790 | 0.82 | CA12 (0.52) | CA12CA1CA2CA9HTT | |
| SCHEMBL8182994 | 0.82 | SMN1; SMN2 (0.42) | CA12CA1CA2CA9HTT | |
| SCHEMBL10952879 | 0.81 | GAA (0.50) | CA12CA1CA2CA9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101720319-A | Thiazolidine derivatives and methods for the preparation thereof | KAINOS MEDICINE INC | 2010-06-02 | — | — | CN | disclosed |
| EP-2118081-A2 | THIAZOLIDINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF | Kainos Medicine, Inc., (KR) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008087560-A2 | THIAZOLIDINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF | KAINOS MEDICINE, INC., (US) | 2008-07-24 | — | — | WO | disclosed |