Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 4/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | KLK1 | P06870 | 3/20 | 0.36 |
| ▸ | KLK6 | Q92876 | 3/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CFD | P00746 | 2/20 | 0.34 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | BPTF | Q12830 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13501533 | 0.83 | CA12 (0.46) | LOXL2PLGTPSAB1PRSS1KLK1 | |
| SCHEMBL13501538 | 0.83 | CA12 (0.46) | LOXL2PLGTPSAB1PRSS1KLK1 | |
| SCHEMBL4444065 | 0.83 | CA12 (0.46) | LOXL2PLGTPSAB1PRSS1KLK1 | |
| SCHEMBL4441635 | 0.77 | CFD (0.50) | LOXL2PLGKLK1KLK6CFD | |
| Hydrochloric Acid SCHEMBL3619634 | 0.76 | CFD (0.49) | LOXL2PLGKLK1KLK6CFD | |
| SCHEMBL4829862 | 0.69 | CA12 (0.48) | CA12CA1CA2CA9HTT | |
| SCHEMBL28511516 | 0.68 | AURKA (0.48) | CA12CA1CA2CA9HTT | |
| SCHEMBL30713077 | 0.68 | AURKA (0.48) | CA12CA1CA2CA9HTT | |
| Hydrochloric Acid SCHEMBL4826620 | 0.68 | CA12 (0.47) | CA12CA1CA2CA9HTT | |
| SCHEMBL904392 | 0.67 | PLG (0.47) | LOXL2PLGTPSAB1PRSS1KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087560-A2 | THIAZOLIDINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF | KAINOS MEDICINE, INC., (US) | 2008-07-24 | — | — | WO | disclosed |