Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 13/20 | 0.63 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1591184 | 0.88 | FLT3 (0.62) | FLT3YTHDC1PDGFRANPC1RAB9A | |
| SCHEMBL12703837 | 0.88 | FLT3 (0.62) | FLT3YTHDC1PDGFRANPC1RAB9A | |
| SCHEMBL4432844 | 0.84 | FLT3 (0.60) | FLT3YTHDC1PDGFRANPC1RAB9A | |
| SCHEMBL4444458 | 0.80 | FLT3 (0.59) | FLT3YTHDC1PDGFRANPC1RAB9A | |
| SCHEMBL4443143 | 0.79 | CSNK1D (0.43) | FLT3PDGFRA | |
| SCHEMBL4438500 | 0.78 | CSNK1D (0.44) | FLT3PDGFRA | |
| SCHEMBL30677295 | 0.77 | FLT3 (0.81) | FLT3YTHDC1PDGFRANPC1RAB9A | |
| SCHEMBL1591541 | 0.72 | FLT3 (0.68) | FLT3YTHDC1PDGFRA | |
| SCHEMBL21967147 | 0.72 | FLT3 (0.60) | FLT3YTHDC1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21967400 | 0.71 | FLT3 (0.59) | FLT3YTHDC1PDGFRANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2124954-A2 | PURINE COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS FOR THE TREATMENT OF PLASMODIUM RELATED DISEASES | IRM LLC (BM) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008094737-A2 | PURINE COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS FOR THE TREATMENT OF PLASMODIUM RELATED DISEASES | IRM LLC (BM) | 2008-08-07 | — | — | WO | disclosed |