Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 7/20 | 0.68 |
| ▸ | APAF1 | O14727 | 1/20 | 0.62 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.62 |
| ▸ | RAD52 | P43351 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | APEX1 | P27695 | 3/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | LSS | P48449 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL28072729 | 1.00 | DNM1 (0.68) | DNM1APAF1HSP90AA1RAD52MEN1 | |
| Bicarbonate SCHEMBL28072719 | 1.00 | DNM1 (0.68) | DNM1APAF1HSP90AA1RAD52MEN1 | |
| Bicarbonate SCHEMBL28072659 | 1.00 | DNM1 (0.68) | DNM1APAF1HSP90AA1RAD52MEN1 | |
| Bicarbonate SCHEMBL28072727 | 1.00 | DNM1 (0.68) | DNM1APAF1HSP90AA1RAD52MEN1 | |
| Bicarbonate SCHEMBL28963197 | 1.00 | DNM1 (0.68) | DNM1APAF1HSP90AA1RAD52MEN1 | |
| Cetrimonium SCHEMBL9739313 | 1.00 | DNM1 (0.68) | DNM1APAF1HSP90AA1RAD52MEN1 | |
| Bicarbonate SCHEMBL28323254 | 1.00 | DNM1 (0.68) | DNM1APAF1HSP90AA1RAD52MEN1 | |
| Bicarbonate SCHEMBL9724761 | 1.00 | DNM1 (0.68) | DNM1APAF1HSP90AA1RAD52MEN1 | |
| Bicarbonate SCHEMBL22630884 | 1.00 | DNM1 (0.68) | DNM1APAF1HSP90AA1RAD52MEN1 | |
| Bicarbonate SCHEMBL28057192 | 1.00 | DNM1 (0.68) | DNM1APAF1HSP90AA1RAD52MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4717720-A1 | CATALYST COMPOSITION, BLOCKED POLYISOCYANATE COMPOSITION, COATING MATERIAL COMPOSITION, COATING FILM, AND METHOD FOR FORMING COATING FILM | Tosoh Corporation (JP) | 2026-04-01 | — | — | EP | disclosed |
| EP-4678676-A1 | BLOCKED POLYISOCYANATE COMPOSITION, CURING AGENT FOR AQUEOUS COATING, AQUEOUS COATING COMPOSITION, AND COATING FILM | Tosoh Corporation (JP) | 2026-01-14 | — | — | EP | disclosed |
| WO-2024262553-A1 | CATALYST COMPOSITION, BLOCKED POLYISOCYANATE COMPOSITION, COATING MATERIAL COMPOSITION, COATING FILM, AND METHOD FOR FORMING COATING FILM | 東ソー株式会社 | 2024-12-26 | — | — | WO | disclosed |
| WO-2024202500-A1 | BLOCKED POLYISOCYANATE COMPOSITION, CURING AGENT FOR AQUEOUS COATING, AQUEOUS COATING COMPOSITION, AND COATING FILM | 東ソー株式会社 | 2024-10-03 | — | — | WO | disclosed |
| US-12012368-B2 | Cage silicate and method for producing the same | NISSAN CHEMICAL CORPORATION (JP) | 2024-06-18 | — | — | US | disclosed |
| US-11999625-B2 | Method of producing layered silicate, and application thereof in production of silica nanosheet and so on | NISSAN CHEMICAL CORPORATION (JP) | 2024-06-04 | — | — | US | disclosed |
| CN-117813334-A | Onium salt, blocking agent dissociation catalyst for blocking isocyanate, blocked isocyanate composition containing blocking agent dissociation catalyst, thermosetting resin composition, cured product, and method for producing same | 广荣化学株式会社 | 2024-04-02 | — | — | CN | disclosed |
| US-20240051834-A1 | METHOD OF PRODUCING LAYERED SILICATE, AND APPLICATION THEREOF IN PRODUCTION OF SILICA NANOSHEET AND SO ON | NISSAN CHEMICAL CORPORATION (JP) | 2024-02-15 | — | — | US | disclosed |
| US-20240051913-A1 | CAGE SILICATE AND METHOD FOR PRODUCING THE SAME | NISSAN CHEMICAL CORPORATION (JP) | 2024-02-15 | — | — | US | disclosed |
| EP-4279454-A1 | CAGE SILICATE AND METHOD FOR PRODUCING SAME | Nissan Chemical Corporation (JP) | 2023-11-22 | — | — | EP | disclosed |
| WO-2023188930-A1 | METHOD FOR PRODUCING LAYERED SILICATE AND APPLICATION THEREOF IN SILICA NANOSHEET PRODUCTION, ETC. | 日産化学株式会社 | 2023-10-05 | — | — | WO | disclosed |
| WO-2023188928-A1 | CAGE SILICATE AND METHOD FOR PRODUCING SAME | 日産化学株式会社 | 2023-10-05 | — | — | WO | disclosed |
| WO-2021256254-A1 | MODIFIED POLYISOCYANATE COMPOSITION AND COATING COMPOSITION USING SAME | 東ソー株式会社 | 2021-12-23 | — | — | WO | disclosed |
| CN-105829375-B | Allophanate-isocyanurateing catalyst, polyisocyanate composition, method for producing the composition, and two-component coating composition | 东曹株式会社 | 2019-09-20 | — | — | CN | disclosed |
| CN-104313634-B | A kind of continuous electrolysis prepares the method for long-chain alkyl ammonium hydroxide | 中国日用化学工业研究院 | 2016-11-30 | — | — | CN | disclosed |
| CN-105829375-A | Allophanate-isocyanurateing catalyst, polyisocyanate composition, method for producing the composition, and two-component coating composition | 东曹株式会社 | 2016-08-03 | — | — | CN | disclosed |
| CN-104313634-A | Method for preparing long-chain alkyl ammonium hydroxide by continuous electrolysis | CHINA RES INST DAILY CHEM IND | 2015-01-28 | — | — | CN | disclosed |
| EP-0839841-B1 | Anti-bacterial water absorbing agent and anti-bacterial water absorbent material | SANYO CHEMICAL IND LTD (JP) | 2009-05-06 | — | — | EP | disclosed |
| US-5981668-A | COMPRISING A WATER ABSORBING RESIN HAVING PENDANT ACID GROUPS, AT LEAST ONE ACID GROUP BEING IN THE FORM OF A QUATERNARY AMMONIUM SALT | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0839841-A2 | Anti-bacterial water absorbing agent and anti-bacterial water absorbent material | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 1998-05-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12012368-B2 | Cage silicate and method for producing the same | SIGMAR1, SAE1, SEM1 | DNM1 2035/4885APAF1 2111/4885HSP90AA1 2128/4885 |
| US-20240051913-A1 | CAGE SILICATE AND METHOD FOR PRODUCING THE SAME | ORAI2, SIGMAR1, SEM1 | DNM1 2074/4885APAF1 2248/4885HSP90AA1 2305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.