Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 9/20 | 0.57 |
| ▸ | MAOB | P27338 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | ROR1 | Q01973 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 3/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | AXL | P30530 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4444327 | 1.00 | CYP19A1 (0.57) | CYP19A1MAOBMAPTNPC1RAB9A | |
| SCHEMBL25437506 | 0.82 | MAOB (0.74) | CYP19A1MAOBMAPTNPC1RAB9A | |
| SCHEMBL25435378 | 0.80 | MAOB (0.56) | CYP19A1MAOBMAPTNPC1RAB9A | |
| SCHEMBL8093202 | 0.76 | CYP19A1 (0.74) | CYP19A1MAOBMAPTNPC1RAB9A | |
| SCHEMBL8093207 | 0.76 | CYP19A1 (0.74) | CYP19A1MAOBMAPTNPC1RAB9A | |
| SCHEMBL4444342 | 0.76 | ROR1 (0.43) | CYP19A1MAOBROR1KDM4EALDH1A1 | |
| SCHEMBL13708477 | 0.74 | ROR1 (0.82) | CYP19A1MAOBNPC1RAB9AROR1 | |
| SCHEMBL22465359 | 0.72 | ROR1 (0.61) | CYP19A1ROR1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL7032379 | 0.72 | CYP19A1 (0.74) | CYP19A1MAOBMAPTNPC1RAB9A | |
| SCHEMBL7032375 | 0.72 | CYP19A1 (0.74) | CYP19A1MAOBMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221568-A1 | Synthesis of Inhibitors of FtsZ | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221568-A1 | Synthesis of Inhibitors of FtsZ | CDC42, CCNB1, CDC20 | CYP19A1 3079/4885MAOB 3443/4885MAPT 1355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.