Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 8/20 | 0.41 |
| ▸ | HTR2A | P28223 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | LIG1 | P18858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25661 | 0.83 | HPGD (0.45) | TSHRGAAADRA2AADRA2BADRA2C | |
| SCHEMBL23216966 | 0.79 | HTR2C (0.51) | TSHRGAAADRA2AADRA2BADRA2C | |
| SCHEMBL4444347 | 0.76 | ADRA2A (0.48) | TSHRGAAADRA2AADRA2BADRA2C | |
| SCHEMBL28627196 | 0.76 | HTR2C (0.55) | TSHRGAAADRA2AADRA2BADRA2C | |
| SCHEMBL31399005 | 0.75 | GAA (0.62) | TSHRGAAHPGDALDH1A1MEN1 | |
| SCHEMBL929686 | 0.75 | GAA (0.62) | TSHRGAAHPGDALDH1A1MEN1 | |
| SCHEMBL11699516 | 0.74 | LIG1 (0.46) | TSHRGAAADRA2AADRA2BADRA2C | |
| SCHEMBL5447967 | 0.73 | HPGD (0.43) | TSHRGAAADRA2AADRA2BADRA2C | |
| SCHEMBL23216493 | 0.72 | HTR2C (0.49) | TSHRGAAADRA2AADRA2BADRA2C | |
| SCHEMBL29782302 | 0.72 | HTR2C (0.49) | TSHRGAAADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8513346-B2 | Flame retardant composition for use in styrenics | CHEMTURA CORPORATION (US) | 2013-08-20 | — | — | US | disclosed |
| US-20120184638-A1 | Flame Retardant Composition for Use in Styrenics | LANXESS SOLUTIONS US INC. | 2012-07-19 | — | — | US | disclosed |
| EP-2115059-A1 | FLAME RETARDANT COMPOSITION FOR USE IN STYRENICS | CHEMTURA CORPORATION (US) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008127753-A1 | FLAME RETARDANT COMPOSITION FOR USE IN STYRENICS | CHEMTURA CORPORATION (US) | 2008-10-23 | — | — | WO | disclosed |
| US-20080221239-A1 | Flame retardant composition for use in styrenics | RECREATIONAL WATER PRODUCTS, INC. | 2008-09-11 | — | — | US | disclosed |
| EP-0023415-A2 | A method of mounting ventilators, lights and the like in sealed relation to an opening and a preformed sealing material for use in such a method | COLT INTERNATIONAL HOLDINGS A.G. (CH) | 1981-02-04 | — | — | EP | disclosed |