SCHEMBL25661

SCHEMBL25661

C=CCOc1ccc(Br)c(Br)c1Br

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.45
ALDH1A1 P00352 1/20 0.45
TSHR P16473 2/20 0.42
GAA P10253 1/20 0.42
MEN1 O00255 1/20 0.42
HTT P42858 1/20 0.42
KMT2A Q03164 1/20 0.42
MAPK1 P28482 2/20 0.40
LIG1 P18858 1/20 0.40
HSD17B10 Q99714 1/20 0.39
CA12 O43570 3/20 0.37
CA1 P00915 3/20 0.37
CA9 Q16790 3/20 0.37
CA2 P00918 1/20 0.37
CA7 P43166 1/20 0.37
ADRA2A P08913 2/20 0.36
ADRA2B P18089 2/20 0.36
ADRA2C P18825 2/20 0.36
KDM4E B2RXH2 1/20 0.36
CYP3A4 P08684 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4444346 0.83 TSHR (0.46) HPGDALDH1A1TSHRGAAMEN1
SCHEMBL11699516 0.82 LIG1 (0.46) HPGDALDH1A1TSHRGAAMEN1
SCHEMBL4444347 0.81 ADRA2A (0.48) HPGDALDH1A1TSHRGAAMEN1
SCHEMBL5447967 0.77 HPGD (0.43) HPGDALDH1A1TSHRGAAMEN1
SCHEMBL245322 0.77 TDP1 (0.34) HPGD
SCHEMBL94045 0.76 TDP1 (0.37) HPGDALDH1A1GAAHTTKDM4E
SCHEMBL23216966 0.76 HTR2C (0.51) HPGDALDH1A1TSHRGAAMEN1
SCHEMBL28691052 0.76 HPGD (0.47) HPGDALDH1A1TSHRGAAMEN1
SCHEMBL2322279 0.74 HPGD (0.59) HPGDALDH1A1TSHRGAAMEN1
SCHEMBL28254022 0.74 ALDH1A1 (0.43) HPGDALDH1A1TSHRGAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 517 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116693779-B Preparation of functional N-phenyl maleimide and application of functional N-phenyl maleimide in ABS resin 四川之江高新材料股份有限公司 2024-09-17 CN claimed
CN-118085483-A Flame-retardant material containing acrylate emulsion and preparation method thereof 浙江睿高新材料股份有限公司 2024-05-28 CN claimed
CN-117986502-A Polymer damping brominating agent, high damping brominated butyl rubber composition and preparation thereof 中国石油天然气股份有限公司 2024-05-07 CN claimed
CN-113646107-B Casting material composition and method for producing casting using same 旭有机材株式会社 2024-05-03 CN claimed
CN-117801187-A Preparation of functional damping brominated grafting agent and damping brominated branched butyl rubber 中国石油天然气股份有限公司 2024-04-02 CN claimed
CN-117659487-A Preparation method of wave-absorbing flame-retardant brown PMI composite foam 湖南兆恒材料科技有限公司 2024-03-08 CN claimed
CN-116693779-A Preparation of functional N-phenyl maleimide and application of functional N-phenyl maleimide in ABS resin 四川之江高新材料股份有限公司 2023-09-05 CN claimed
CN-116463016-A Heat-resistant UV flame-retardant coating 南通煜源科技有限公司 2023-07-21 CN claimed
EP-3936556-B1 FLAME-RETARDANT, MOISTURE-CURED WIRE AND CABLE CONSTRUCTIONS WITH IMPROVED GLANCING IMPACT PERFORMANCE DOW GLOBAL TECHNOLOGIES LLC (US) 2023-06-21 EP claimed
CN-110291137-B Moisture-cured flame-retardant wire and cable constructions with improved glancing impact properties 陶氏环球技术有限责任公司 2023-04-25 CN claimed
US-5106522-A Liquid hydrophobic vehicle for electro-rheological fluid NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1992-04-21 US claimed
US-4965021-A HALOGENATED ORGANIC COMPOUNDS BROMINE COMPOUNDS LIMITED (IL) 1990-10-23 US claimed
US-4849134-A FOR POLYMERS, HALOGENATED COMPOUNDS BROMINE COMPOUNDS LIMITED (IL) 1989-07-18 US claimed
EP-0223539-A2 Granular flame retardant agents, process for their preparation and method and materials obtained thereby Bromine Compounds Ltd. (IL) 1987-05-27 EP claimed
US-4323662-A Thermosetting resin compositions comprising bismaleimides and alkenylaniline derivatives MITSUI TOATSU CHEMICALS, INC. (JP) 1982-04-06 US claimed
US-4173561-A STYRENE RESIN, HALOGEN COMPOUND, INORGANIC HYDRATE, MAGNESIUM COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1979-11-06 US claimed
US-4104698-A CAPACITOR, TRIBORMOPHENOL ALKYL ETHER SUMITOMO DUREZ COMPANY, LTD. (JP) 1978-08-01 US claimed
US-4032490-A MICROCRYSTALLINE; TRIBROMOPHENOL ALKYL ETHER AND A THERMPOLASTIC RESIN SUMITOMO DUREZ COMPANY, LTD. (JA) 1977-06-28 US claimed
US-4027063-A CIRCUIT BOARDS, METH-ACRYLOYLOXY-TERMINATED BUTADIENE RESIN, HALOGEN CONTAINING MONOMER AND UNSATURATED ANHYDRIDE SONY CORPORATION (JA) 1977-05-31 US claimed
US-3985661-A LUBRICANT-ABSORBING POWDER CARRIER SUMITOMO ELECTRIC INDUSTRIES, LTD. (JA) 1976-10-12 US claimed