Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 11/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 11/20 | 0.36 |
| ▸ | MAOA | P21397 | 5/20 | 0.33 |
| ▸ | MAOB | P27338 | 4/20 | 0.33 |
| ▸ | PTPRF | P10586 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | PRF1 | P14222 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL787167 | 0.78 | PTPRF (0.30) | PTPRF | |
| SCHEMBL540690 | 0.68 | PTPRF (0.42) | PTPRF | |
| SCHEMBL8468103 | 0.65 | PTPRF (0.36) | MAOAMAOBPTPRF | |
| SCHEMBL4378541 | 0.61 | MAOA (0.38) | PDE3BPDE3AMAOAMAOBPRF1 | |
| SCHEMBL533284 | 0.61 | GSTP1 (0.39) | MAOAMAOB | |
| SCHEMBL66015 | 0.60 | MAOA (0.37) | MAOAMAOB | |
| SCHEMBL8781662 | 0.60 | GSTP1 (0.38) | MAOAMAOB | |
| SCHEMBL2479036 | 0.60 | MAOA (0.40) | MAOALMNA | |
| SCHEMBL2111856 | 0.60 | MAOA (0.37) | MAOAMAOB | |
| SCHEMBL31138104 | 0.60 | MAOA (0.37) | MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4294859-B2 | — | — | 2009-07-15 | — | — | JP | claimed |
| JP-2002514661-A | — | — | 2002-05-21 | — | — | JP | claimed |
| EP-1023369-B1 | DEPOLYMERIZATION PROCESS FOR RECYCLING POLYESTERS | EASTMAN CHEM CO (US) | 2002-01-16 | — | — | EP | claimed |
| US-6136869-A | USING ALCOHOL SUCH AS METHANOL, ETHANOL AND, OR PROPANOL | EASTMAN CHEMICAL COMPANY (US) | 2000-10-24 | — | — | US | claimed |
| EP-1023369-A1 | DEPOLYMERIZATION PROCESS FOR RECYCLING POLYESTERS | EASTMAN CHEMICAL COMPANY (US) | 2000-08-02 | — | — | EP | claimed |
| WO-1999020684-A1 | DEPOLYMERIZATION PROCESS FOR RECYCLING POLYESTERS | EASTMAN CHEMICAL COMPANY (US) | 1999-04-29 | — | — | WO | claimed |