SCHEMBL4378541

SCHEMBL4378541

Cc1ccc2cc1C(=O)OCCOC2=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
PRF1 P14222 1/20 0.34
GRIA1 P42261 1/20 0.34
CACNG8 Q8WXS5 1/20 0.34
LMNA P02545 2/20 0.34
HTT P42858 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
PDE3B Q13370 3/20 0.33
PDE3A Q14432 3/20 0.33
ALDH1A1 P00352 1/20 0.33
CD274 Q9NZQ7 3/20 0.33
PDCD1 Q15116 2/20 0.33
PTPRC P08575 1/20 0.33
MAPK14 Q16539 1/20 0.32
GRIA2 P42262 1/20 0.32
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
MAPT P10636 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6034665 0.79 ALDH1A1 (0.37) MAOAMAOBLMNAHTTPDE3B
SCHEMBL4557119 0.76 PRF1 (0.33) MAOAMAOBPRF1LMNAHTT
SCHEMBL5009684 0.74 ALOX5 (0.43) MAOAMAOBPRF1LMNASMN1; SMN2
SCHEMBL17628649 0.73 ITGB2 (0.43) MAOAMAOBPRF1LMNAHTT
SCHEMBL3874923 0.73 ITGB2 (0.43) MAOAMAOBPRF1LMNAHTT
SCHEMBL22419 0.73 ITGB2 (0.43) MAOAMAOBPRF1LMNAHTT
SCHEMBL5520002 0.73 PRF1 (0.38) MAOAMAOBPRF1LMNAHTT
SCHEMBL2232672 0.73 KMT2A (0.36) LMNAHTTALDH1A1MEN1KMT2A
SCHEMBL36556 0.73 GSTP1 (0.45) SMN1; SMN2ALDH1A1MEN1MAPTKMT2A
SCHEMBL7108757 0.73 MAOA (0.46) MAOAMAOBPRF1LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3169611-A1 A DIE-CUT LID AND ASSOCIATED CONTAINER AND METHOD Koninklijke Douwe Egberts B.V. (NL) 2017-05-24 EP claimed
WO-2016009258-A1 A DIE-CUT LID AND ASSOCIATED CONTAINER AND METHOD KRAFT FOODS R&D, INC. (US) 2016-01-21 WO claimed
EP-2044601-A2 THERMALLY IMAGEABLE DIELECTRIC LAYERS, THERMAL TRANSFER DONORS AND RECEIVERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-04-08 EP claimed
WO-2008010982-A2 THERMALLY IMAGEABLE DIELECTRIC LAYERS, THERMAL TRANSFER DONORS AND RECEIVERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-01-24 WO claimed