Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL27888561 | 0.92 | LMNA (0.43) | LMNATHRBTSHRALDH1A1 | |
| SCHEMBL8272284 | 0.91 | — | — | |
| SCHEMBL6375588 | 0.91 | — | — | |
| SCHEMBL157863 | 0.91 | — | — | |
| Alcohol SCHEMBL4557597 | 0.90 | LMNA (0.38) | LMNATHRB | |
| Propylene Glycol SCHEMBL27888542 | 0.87 | TDP1 (0.50) | LMNATHRBTSHR | |
| Di(Hydroxyethyl)Ether SCHEMBL4830560 | 0.83 | ALDH1A1 (0.50) | LMNATHRBTSHRALDH1A1 | |
| SCHEMBL25786758 | 0.80 | LMNA (0.43) | LMNATHRB | |
| SCHEMBL6380672 | 0.79 | LMNA (0.38) | LMNATHRBALDH1A1 | |
| SCHEMBL12650465 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663916-B1 | METHOD FOR CATALYTIC DEOXYGENATION OF PROCESS FLUIDS OF OLEFIN DIMERIZATION PROCESSES | NESTE OIL OYJ (FI) | 2009-07-01 | — | — | EP | disclosed |