SCHEMBL4444597

SCHEMBL4444597

Oc1c(Br)c(Br)c(Cl)c(Br)c1Br

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.60
HSD17B10 Q99714 4/20 0.60
ALDH1A1 P00352 2/20 0.60
MAPK1 P28482 2/20 0.60
ALOX15 P16050 1/20 0.60
RECQL P46063 1/20 0.60
HIF1A Q16665 1/20 0.60
CA1 P00915 3/20 0.50
CA2 P00918 3/20 0.50
CA4 P22748 3/20 0.50
CA6 P23280 3/20 0.50
TSHR P16473 3/20 0.41
MEN1 O00255 1/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
KMT2A Q03164 1/20 0.41
PTPN1 P18031 2/20 0.36
DRD4 P21917 2/20 0.35
CASP1 P29466 1/20 0.33
MAOA P21397 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4444595 0.83 HPGD (0.56) HPGDHSD17B10ALDH1A1MAPK1ALOX15
SCHEMBL8647156 0.83 HPGD (0.56) HPGDHSD17B10ALDH1A1MAPK1ALOX15
SCHEMBL48572 0.80 ALDH1A1 (0.90) HPGDHSD17B10ALDH1A1MAPK1ALOX15
SCHEMBL28942555 0.80
SCHEMBL11392755 0.80 HPGD (0.53) HPGDHSD17B10ALDH1A1MAPK1ALOX15
SCHEMBL11572614 0.79 HPGD (0.50) HPGDHSD17B10ALDH1A1MAPK1ALOX15
Pentabromophenol SCHEMBL268325 0.76 ALOX15 (1.00) HPGDHSD17B10ALDH1A1MAPK1ALOX15
SCHEMBL10998008 0.73 HPGD (0.44) HPGDHSD17B10ALDH1A1MAPK1ALOX15
SCHEMBL127379 0.72 ALOX15 (0.91) HPGDHSD17B10ALDH1A1MAPK1ALOX15
Pentabromophenol SCHEMBL11697558 0.72 ALOX15 (0.91) HPGDHSD17B10ALDH1A1MAPK1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8513346-B2 Flame retardant composition for use in styrenics CHEMTURA CORPORATION (US) 2013-08-20 US disclosed
US-20120184638-A1 Flame Retardant Composition for Use in Styrenics LANXESS SOLUTIONS US INC. 2012-07-19 US disclosed
EP-2115059-A1 FLAME RETARDANT COMPOSITION FOR USE IN STYRENICS CHEMTURA CORPORATION (US) 2009-11-11 EP disclosed
WO-2008127753-A1 FLAME RETARDANT COMPOSITION FOR USE IN STYRENICS CHEMTURA CORPORATION (US) 2008-10-23 WO disclosed
US-20080221239-A1 Flame retardant composition for use in styrenics RECREATIONAL WATER PRODUCTS, INC. 2008-09-11 US disclosed
US-4290846-A Method of protecting organic or inorganic material from attack by microorganisms CIBA-GEIGY CORPORATION (US) 1981-09-22 US disclosed
US-4285971-A FUNGICIDES, SLIMICIDES, BACTERICIDES, AND ALGICIDES; TEXTILES; PAPERMAKING; WOOD CIBA-GEIGY CORPORATION (US) 1981-08-25 US disclosed
EP-0008061-B1 HALOGENATED PHENOLIC ESTERS, GERM-KILLING COMPOSITIONS CONTAINING THEM, AND THEIR USE CIBA-GEIGY AG (CH) 1981-07-29 EP disclosed
EP-0008061-A1 Halogenated phenolic esters, germ-killing compositions containing them, and their use CIBA-GEIGY AG (CH) 1980-02-20 EP disclosed