Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6655623 | 0.87 | — | — | |
| SCHEMBL29023838 | 0.85 | — | — | |
| SCHEMBL9004287 | 0.82 | LMNA (0.35) | ALOX15LMNATSHRCHRM2CHRM4 | |
| SCHEMBL9004319 | 0.79 | CA1 (0.38) | LMNATSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL29728562 | 0.78 | ALOX15 (0.43) | ALOX15LMNATSHRCHRM2CHRM4 | |
| SCHEMBL224781 | 0.78 | — | — | |
| SCHEMBL25200468 | 0.76 | — | — | |
| SCHEMBL88486 | 0.76 | — | — | |
| SCHEMBL7297893 | 0.76 | — | — | |
| SCHEMBL473155 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009129181-A1 | PROPANEDIOL-DICARBAMATE DERIVATIVES | CONCERT PHARMACEUTICALS INC. (US) | 2009-10-22 | — | — | WO | disclosed |
| WO-2009129181-A1 | PROPANEDIOL-DICARBAMATE DERIVATIVES | CONCERT PHARMACEUTICALS INC. (US) | 2009-10-22 | — | — | WO | disclosed |