Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL88488 | 1.00 | — | — | |
| Bicarbonate SCHEMBL5083789 | 0.86 | — | — | |
| Acetic Acid SCHEMBL10353591 | 0.83 | FFAR3 (0.50) | FFAR3TSHRCA2TP53CHRM1 | |
| Oxalic Acid SCHEMBL29895907 | 0.83 | FFAR3 (0.41) | FFAR3TSHRCA2SLC1A3SLC1A2 | |
| Oxalic Acid SCHEMBL8730478 | 0.83 | FFAR3 (0.41) | FFAR3TSHRCA2SLC1A3SLC1A2 | |
| Acetic Acid SCHEMBL1362080 | 0.83 | — | — | |
| Propionic Acid SCHEMBL1362098 | 0.80 | FFAR3 (0.67) | FFAR3TSHRTP53HDAC1HDAC2 | |
| Carbamic Acid SCHEMBL9280663 | 0.80 | — | — | |
| Propionic Acid SCHEMBL1362611 | 0.80 | FFAR3 (0.67) | FFAR3TSHRTP53HDAC1HDAC2 | |
| SCHEMBL4958367 | 0.80 | TSHR (0.39) | FFAR3TSHRCA2SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009129181-A1 | PROPANEDIOL-DICARBAMATE DERIVATIVES | CONCERT PHARMACEUTICALS INC. (US) | 2009-10-22 | — | — | WO | disclosed |
| WO-2009129181-A1 | PROPANEDIOL-DICARBAMATE DERIVATIVES | CONCERT PHARMACEUTICALS INC. (US) | 2009-10-22 | — | — | WO | disclosed |