Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL29895907 | 1.00 | FFAR3 (0.41) | FFAR3TSHRTP53HDAC1HDAC2 | |
| Bicarbonate SCHEMBL5083789 | 0.89 | — | — | |
| Acetic Acid SCHEMBL1362080 | 0.86 | — | — | |
| Acetic Acid SCHEMBL10353591 | 0.86 | FFAR3 (0.50) | FFAR3TSHRTP53HDAC1HDAC2 | |
| Propionic Acid SCHEMBL1362098 | 0.83 | FFAR3 (0.67) | FFAR3TSHRTP53HDAC1HDAC2 | |
| Carbamic Acid SCHEMBL88488 | 0.83 | — | — | |
| Carbamic Acid SCHEMBL4444664 | 0.83 | ACHE (0.47) | FFAR3TSHRTP53HDAC1HDAC2 | |
| Oxalic Acid SCHEMBL28309748 | 0.83 | TSHR (0.67) | FFAR3TSHRTP53HDAC1HDAC2 | |
| SCHEMBL4958367 | 0.83 | TSHR (0.39) | FFAR3TSHRTP53HDAC1HDAC2 | |
| Propionic Acid SCHEMBL1362611 | 0.83 | FFAR3 (0.67) | FFAR3TSHRTP53HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102533393-A | Molybdenum disulfide lubrication crayon | TIANJIN TIANMA GREASE CHEMICAL CO LTD | 2012-07-04 | — | — | CN | disclosed |
| EP-0819134-A1 | COVALENTLY CROSS-LINKED OLIGONUCLEOTIDES, METHOD FOR PREPARING SAME, AND SYNTHON USED THEREIN | GENSET SA (FR) | 1998-01-21 | — | — | EP | disclosed |
| WO-1996031523-A1 | COVALENTLY CROSS-LINKED OLIGONUCLEOTIDES, METHOD FOR PREPARING SAME, AND SYNTHON USED THEREIN | GENSET (FR) | 1996-10-10 | — | — | WO | disclosed |