Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.45 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7252416 | 0.87 | NPC1 (0.48) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL4058393 | 0.85 | ADAM17 (0.60) | OPRL1ADAM17MMP13 | |
| SCHEMBL6633312 | 0.82 | GPBAR1 (0.53) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL5220040 | 0.81 | NPC1 (0.44) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9582777 | 0.76 | ALDH1A1 (0.56) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL19422787 | 0.75 | NPC1 (0.49) | NPC1ALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL7069563 | 0.74 | PPARA (0.60) | — | |
| SCHEMBL3968933 | 0.73 | POLB (0.47) | NPC1ALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL3967858 | 0.73 | ADAM17 (0.58) | ADAM17MMP13 | |
| SCHEMBL15009057 | 0.73 | ALDH1A1 (0.57) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397137-B1 | HYDANTION DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | BRISTOL MYERS SQUIBB CO (US) | 2009-10-14 | — | — | EP | disclosed |