Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 5/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TDP2 | O95551 | 6/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CASP9 | P55211 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.39 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 2/20 | 0.37 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1509853 | 0.79 | — | — | |
| SCHEMBL442673 | 0.78 | TDP2 (0.43) | AHRPDK2TDP2CASP3CASP7 | |
| Hydrochloric Acid SCHEMBL10924919 | 0.75 | — | — | |
| SCHEMBL6379887 | 0.71 | AHR (0.70) | AHRPDK2ALDH1A1TDP2CASP3 | |
| SCHEMBL1235044 | 0.71 | AHR (0.70) | AHRPDK2ALDH1A1TDP2CASP3 | |
| Barbituric Acid SCHEMBL4560317 | 0.69 | ALDH1A1 (0.55) | AHRPDK2ALDH1A1TDP2CASP3 | |
| Barbituric Acid SCHEMBL9941322 | 0.69 | — | — | |
| Barbituric Acid SCHEMBL38707 | 0.69 | — | — | |
| SCHEMBL1603679 | 0.69 | GSK3B (0.40) | ALDH1A1CYP2C9CASP3CASP7CASP6 | |
| Barbituric Acid SCHEMBL11379882 | 0.67 | ALDH1A1 (0.52) | AHRPDK2ALDH1A1TDP2CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120062228-A1 | PREPARATION OF POLYAMIDE BLOCK COPOLYMERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-15 | — | — | US | disclosed |
| US-8063169-B2 | Preparation of polyamide block copolymers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-11-22 | — | — | US | disclosed |
| US-7635747-B2 | Using mixtures or adducts of N-heterocyclic carbenes with metal amides or metal alkoxides as catalysts; the catalysts are stable at polymerization temperatures, and the polymerization is rapid, resulting in high monomer conversion, high molecular weight | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-12-22 | — | — | US | disclosed |
| US-7514499-B2 | Ring opening polymerization of cyclic amides using N-heterocyclic carbene catalysts | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-04-07 | — | — | US | disclosed |
| US-20070293629-A1 | PREPARATION OF POLAMIDE BLOCK COPOLYMERS | E. I. DU PONT DE NEMOURS AND COMPANY | 2007-12-20 | — | — | US | disclosed |