SCHEMBL4444957

SCHEMBL4444957

COC(Oc1cccc(Oc2ccc([N+](=O)[O-])cc2)c1)=C(C(=O)O)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.59
FFAR1 O14842 2/20 0.57
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
CRHBP P24387 2/20 0.50
CRHR2 Q13324 2/20 0.50
ALDH1A1 P00352 1/20 0.47
FAAH O00519 1/20 0.47
MGLL Q99685 1/20 0.47
RAB9A P51151 1/20 0.47
MAPT P10636 2/20 0.45
HTT P42858 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
PGR P06401 1/20 0.45
LPAR1 Q92633 1/20 0.44
LPAR5 Q9H1C0 1/20 0.44
LPAR3 Q9UBY5 1/20 0.44
SRD5A2 P31213 1/20 0.44
TLR4 O00206 1/20 0.44
TLR2 O60603 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4444955 0.87 KDM4E (0.63) KDM4EFFAR1MEN1KMT2ACRHBP
SCHEMBL2107666 0.77 KDM4E (0.62) KDM4EFFAR1MEN1KMT2ACRHBP
SCHEMBL31504019 0.77 KDM4E (0.72) KDM4EFFAR1MEN1KMT2ACRHBP
SCHEMBL4454902 0.77 MEN1 (0.54) MEN1KMT2AALDH1A1RAB9AMAPT
SCHEMBL203585 0.76 KDM4E (0.51) KDM4EFFAR1MEN1KMT2ACRHBP
SCHEMBL9063379 0.76 KDM4E (0.51) KDM4EFFAR1MEN1KMT2ACRHBP
SCHEMBL6206065 0.76 TSHR (0.47) KMT2AALDH1A1RAB9AMAPTHTT
SCHEMBL177838 0.75 KDM4E (1.00) KDM4EFFAR1MEN1KMT2ACRHBP
SCHEMBL7632953 0.74 ALDH1A1 (0.77) KDM4EFFAR1MEN1KMT2ACRHBP
SCHEMBL27188054 0.74 ALDH1A1 (0.77) KDM4EFFAR1MEN1KMT2ACRHBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090223408-A1 Use of Sub-Micron Copper Salt Particles in Wood Preservation PHIBROWOOD, LLC (US) 2009-09-10 US disclosed
EP-1830989-A2 USE OF SUB-MICRON COPPER SALT PARTICLES IN WOOD PRESERVATION Phibro-Tech, Inc. (US) 2007-09-12 EP disclosed
WO-2006065684-A2 USE OF SUB-MICRON COPPER SALT PARTICLES IN WOOD PRESERVATION PHIBRO-TECH, INC. (US) 2006-06-22 WO disclosed
US-20060062926-A1 Use of sub-micron copper salt particles in wood preservation KOPPERS INC. (F/K/A KOPPERS INDUSTRIES, INC) 2006-03-23 US disclosed