SCHEMBL4445035

SCHEMBL4445035

CCOC(=O)c1c(CSc2ccccc2)n(C)c2cc(Br)c(O)cc12

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 10/20 0.74
MEN1 O00255 1/20 0.74
KMT2A Q03164 1/20 0.74
GAA P10253 2/20 0.64
MLNR O43193 1/20 0.64
NR1I2 O75469 1/20 0.64
CHRM2 P08172 1/20 0.64
CHRM1 P11229 1/20 0.64
ADRA2B P18089 1/20 0.64
ADRA2C P18825 1/20 0.64
SLC6A2 P23975 1/20 0.64
HTR2A P28223 1/20 0.64
HTR2C P28335 1/20 0.64
ADORA2A P29274 1/20 0.64
SLC6A4 P31645 1/20 0.64
PTGS2 P35354 1/20 0.64
HRH1 P35367 1/20 0.64
DRD3 P35462 1/20 0.64
SLC6A3 Q01959 1/20 0.64
PDE4D Q08499 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31693257 0.90 ALOX5 (0.75) ALOX5MEN1KMT2AGAAMLNR
SCHEMBL13953869 0.89 ALOX5 (0.73) ALOX5MEN1KMT2AGAAMLNR
SCHEMBL13953830 0.89 ALOX5 (0.73) ALOX5MEN1KMT2AGAAMLNR
SCHEMBL2857744 0.88 KMT2A (0.70) ALOX5MEN1KMT2AGAAMLNR
SCHEMBL2796202 0.88 ALOX5 (0.60) ALOX5MEN1KMT2AGAAMLNR
SCHEMBL28752891 0.88 ALOX5 (0.58) ALOX5MEN1KMT2AGAAMLNR
SCHEMBL27600510 0.87 ALDH1A1 (0.57) ALOX5MEN1KMT2AGAAMLNR
SCHEMBL13954020 0.86 ALOX5 (0.69) ALOX5MEN1KMT2AGAAMLNR
SCHEMBL13953832 0.86 ALOX5 (0.69) ALOX5MEN1KMT2AGAAMLNR
SCHEMBL31693220 0.86 ALOX5 (0.58) ALOX5MEN1KMT2AGAAMLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 450 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260108619-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2026-04-23 US claimed
CN-119613209-A Preparation method of modified nano silicon powder coated by polymer 中国人民解放军空军工程大学 2025-03-14 CN claimed
CN-118724745-A Asymmetric chiral gel factor for supermolecule assembly and preparation method and application thereof 河南大学 2024-10-01 CN claimed
CN-118668127-A High-strength and high-purity cold stamping die steel and preparation method thereof 宝武特种冶金有限公司 2024-09-20 CN claimed
CN-117586173-B Preparation method of arbidol 石家庄中硕制药有限公司 2024-07-12 CN claimed
CN-117586173-A Preparation method of arbidol 石家庄中硕制药有限公司 2024-02-23 CN claimed
CN-117579003-A High-precision instrument amplifier based on offset calibration of analog-digital hybrid architecture 西安电子科技大学 2024-02-20 CN claimed
EP-4301742-A1 TYPE-II PHOTOINITIATORS ARKEMA FRANCE (FR) 2024-01-10 EP claimed
CN-114507202-B Phellinin compound and preparation method and application thereof 海南大学 2023-10-03 CN claimed
CN-116466011-B Detection method of arbidol hydrochloride related substances and application thereof 则正(上海)生物科技有限公司 2023-09-12 CN claimed
CN-114507202-A Morusin compound and preparation method and application thereof 海南大学 2022-05-17 CN claimed
CN-111542637-B High-strength austenite-based high-manganese steel material and manufacturing method thereof 株式会社POSCO 2022-05-10 CN claimed
CN-114397375-A Method for detecting related substances of arbidol hydrochloride intermediate 石家庄四药有限公司 2022-04-26 CN claimed
CN-111269168-B Preparation method of arbidol intermediate 苏州敬业医药化工有限公司 2022-04-01 CN claimed
CN-111533677-A Method for synthesizing arbidol hydrochloride intermediate 大连万福制药有限公司 2020-08-14 CN claimed
CN-111269168-A Preparation method of arbidol intermediate 苏州敬业医药化工有限公司 2020-06-12 CN claimed
CN-106083691-A A kind of preparation method of arbidol HCl 山东罗欣药业集团股份有限公司 2016-11-09 CN claimed
US-20090326037-A1 Medicinal Agent For Treating Viral Infections ZAKRYTOE AKTSIONERNOE OBSCHESTVO "MASTERKLONA" (RU) 2009-12-31 US claimed
EP-1970061-A1 MEDICINAL AGENT FOR TREATING VIRAL INFECTIONS Zakrytoe Aktsionernoe Obschestvo "Masterklon" (RU) 2008-09-17 EP claimed
US-5198552-A Preparation by bromination, sulfiding, aminomethylation NAUCHNO-ISSLEDOVATELSKY INSTITUT MEDITSINSKOI RADIOLOGII AKADEMII MEDITSINSKIKH NAUK SSSR (RU) 1993-03-30 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090326037-A1 Medicinal Agent For Treating Viral Infections ACE, HAVCR2, MME ALOX5 1451/4885MEN1 2825/4885KMT2A 2362/4885
US-20260108619-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS DCLRE1A, CCR3, CCR8 ALOX5 4247/4885MEN1 2393/4885KMT2A 3633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.