Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 16/20 | 0.71 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.46 |
| ▸ | MYLK | Q15746 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4452891 | 0.99 | NSD2 (0.71) | NSD2TTRCYP3A4KDM4ECYP1A2 | |
| SCHEMBL4445041 | 0.86 | NSD2 (0.67) | NSD2KDM4E | |
| Hydrochloric Acid SCHEMBL4450842 | 0.85 | NSD2 (0.68) | NSD2KDM4E | |
| SCHEMBL4445013 | 0.83 | NSD2 (1.00) | NSD2CYP3A4KDM4ECYP2D6CYP2C19 | |
| SCHEMBL4489080 | 0.83 | NSD2 (0.49) | NSD2CYP3A4KDM4ECYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL4445433 | 0.82 | NSD2 (1.00) | NSD2CYP3A4KDM4ECYP2D6CYP2C19 | |
| SCHEMBL4445049 | 0.81 | NSD2 (0.76) | NSD2 | |
| SCHEMBL4448428 | 0.81 | NSD2 (0.80) | NSD2TTR | |
| Hydrochloric Acid SCHEMBL4443383 | 0.80 | NSD2 (0.77) | NSD2 | |
| SCHEMBL4453024 | 0.80 | NSD2 (0.78) | NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547716-B2 | Sulfonamide derivatives | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2009-06-16 | — | — | US | claimed |