SCHEMBL44451

SCHEMBL44451

C=CC(=O)OCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.46
ALDH1A1 P00352 4/20 0.46
TP53 P04637 3/20 0.46
HIF1A Q16665 3/20 0.46
CYP3A4 P08684 2/20 0.46
HSD17B10 Q99714 1/20 0.46
HPGD P15428 1/20 0.42
THRB P10828 3/20 0.39
MAPK1 P28482 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27085680 1.00 TSHR (0.46) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL1537033 1.00 TSHR (0.46) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL347405 1.00 TSHR (0.46) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL1536968 1.00 TSHR (0.46) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL2462848 1.00 TSHR (0.46) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL2988873 1.00 TSHR (0.46) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL1536995 1.00 TSHR (0.46) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL708916 1.00 TSHR (0.46) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL1286343 1.00 TSHR (0.46) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL1536868 1.00 TSHR (0.46) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2331 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146120-A1 COPOLYMER FOR SEPARATOR AND SECONDARY BATTERY COMPRISING SAME HANSOL CHEMICAL CO., LTD (KR) 2026-05-28 US claimed
US-20260126356-A1 SELECTIVE LIQUID TRANSPORT SYSTEM AND PROCESS The Board of Regents for the Oklahoma Agricultural and Mechanical Colleges (US) 2026-05-07 US claimed
EP-4735935-A2 SURFACE ACTIVATED CHEMICAL VAPOR DEPOSITION AND USES THEREOF Gvd Corporation (US) 2026-05-06 EP claimed
EP-4735933-A2 SURFACE ACTIVATED CHEMICAL VAPOR DEPOSITION AND USES THEREOF Gvd Corporation (US) 2026-05-06 EP claimed
EP-4735934-A2 SURFACE ACTIVATED CHEMICAL VAPOR DEPOSITION AND USES THEREOF Gvd Corporation (US) 2026-05-06 EP claimed
EP-3573461-B1 ANTIMICROBIAL, NON-THROMBOGENIC POLYMER COMPOSITIONS LUBRIZOL ADVANCED MAT INC (US) 2026-04-22 EP claimed
US-12600881-B2 Composition for forming hard coating layer, hard coating layer using the composition, and laminate comprising the hard coating layer DONGJIN SEMICHEM CO., LTD. (KR) 2026-04-14 US claimed
US-12516162-B2 Siloxane exchange chemistry for vitrimers THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-01-06 US claimed
US-20250328075-A1 PHOTOCURABLE COMPOSITION FOR FORMING AN IMPRINT LITHOGRAPHY TEMPLATE CANON KK (JP) 2025-10-23 US claimed
EP-4606828-A1 COPOLYMER FOR SEPARATOR AND SECONDARY BATTERY COMPRISING SAME Hansol Chemical Co., Ltd (KR) 2025-08-27 EP claimed
EP-0449274-A1 Fluoroacrylic polymer having lubricating effect and thermoplastic resin composition comprising same MITSUBISHI RAYON COMPANY, LTD. (JP) 1991-10-02 EP claimed
EP-0425436-A2 Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof CIBA-GEIGY AG (CH) 1991-05-02 EP claimed
US-5010141-A Heat- or UV-curable acrylic resins; coatings; films; biocompatible, water-swelling, oxygen-permeable contact lenses CIBA-GEIGY CORPORATION (US) 1991-04-23 US claimed
EP-0228193-B1 NON-HYDROUS SOFT CONTACT LENS AND PROCESS FOR PRODUCING THE SAME JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1990-10-31 EP claimed
US-4882403-A Non-hydrous soft contact lens and process for producing the same JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1989-11-21 US claimed
US-4812337-A METALLIC PIGMENT BASE COAT, CLEAR TOP COAT KANSAI PAINT COMPANY, LIMITED (JP) 1989-03-14 US claimed
US-4737556-A CROSSLINKED COPOLYMERS OF FLUOROALKYL ACRYLIC ESTERS; UNNECESSARY TO STERILIZE BY BOILING; ANTISOILANTS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1988-04-12 US claimed
US-4732941-A POLYMER ADDED AS STABILIZER KANSAI PAINT COMPANY, LIMITED (JP) 1988-03-22 US claimed
EP-0228193-A1 Non-hydrous soft contact lens and process for producing the same JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1987-07-08 EP claimed
EP-0183989-A2 Fluorine-containing graft copolymer and adhesive and composite membrane made thereof SAGAMI CHEMICAL RESEARCH CENTER (JP) 1986-06-11 EP claimed