Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.83 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.83 |
| ▸ | TSHR | P16473 | 1/20 | 0.83 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14519310 | 0.92 | CYP3A4 (0.80) | ALDH1A1CYP3A4TSHRHPGDMEN1 | |
| SCHEMBL9958244 | 0.91 | CYP3A4 (1.00) | ALDH1A1CYP3A4TSHRHPGDMEN1 | |
| Piperonyl Butoxide SCHEMBL29386186 | 0.91 | CYP3A4 (1.00) | ALDH1A1CYP3A4TSHRHPGDMEN1 | |
| Piperonyl Butoxide SCHEMBL6561910 | 0.91 | CYP3A4 (1.00) | ALDH1A1CYP3A4TSHRHPGDMEN1 | |
| Piperonyl Butoxide SCHEMBL1517385 | 0.91 | CYP3A4 (1.00) | ALDH1A1CYP3A4TSHRHPGDMEN1 | |
| Piperonyl Butoxide SCHEMBL5490 | 0.91 | CYP3A4 (1.00) | ALDH1A1CYP3A4TSHRHPGDMEN1 | |
| Piperonyl Butoxide SCHEMBL1925871 | 0.89 | CYP3A4 (0.97) | ALDH1A1CYP3A4TSHRHPGDMEN1 | |
| Piperonyl Butoxide SCHEMBL11895771 | 0.89 | CYP3A4 (0.97) | ALDH1A1CYP3A4TSHRHPGDMEN1 | |
| Piperonyl Butoxide SCHEMBL9155914 | 0.89 | CYP3A4 (0.97) | ALDH1A1CYP3A4TSHRHPGDMEN1 | |
| Piperonyl Butoxide SCHEMBL317347 | 0.89 | CYP3A4 (0.97) | ALDH1A1CYP3A4TSHRHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090209605-A1 | NEMATICIDAL COMPOSITIONS | DEVGEN N.V. (BE) | 2009-08-20 | — | — | US | disclosed |
| US-20080146445-A1 | Nematicidal Compositions | DEVGEN NV (BE) | 2008-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209605-A1 | NEMATICIDAL COMPOSITIONS | ACHE, DNPH1, NANP | ALDH1A1 4082/4885CYP3A4 2951/4885TSHR 4743/4885 |
| US-20080146445-A1 | Nematicidal Compositions | ACHE, DNPH1, NANP | ALDH1A1 4082/4885CYP3A4 2951/4885TSHR 4743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.