Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 5/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.54 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3227594 | 0.90 | PDE4A (0.55) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL315739 | 0.86 | HSD17B10 (0.56) | HPGDCYP2C9KDM4EHSD17B10POLB | |
| SCHEMBL3223903 | 0.79 | PDE4A (0.55) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL19090458 | 0.79 | ALDH1A1 (0.55) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL3232066 | 0.78 | PDE4A (0.52) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL6944694 | 0.78 | SMN1; SMN2 (0.56) | HPGDCYP2C9HSD17B10POLBRAB9A | |
| SCHEMBL4445212 | 0.77 | KDM4E (0.51) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL3231032 | 0.76 | PDE4A (0.50) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL5085665 | 0.75 | MAPK1 (0.56) | HPGDCYP2C9HSD17B10POLBRAB9A | |
| SCHEMBL4461676 | 0.75 | ADORA1 (0.49) | PDE4AADORA2APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112088010-A | Compositions and methods for treating vaginal dryness | 宝洁公司 | 2020-12-15 | — | — | CN | disclosed |
| US-20090220968-A1 | Methods and Apparatus for Near Field Irradiation | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2009-09-03 | — | — | US | disclosed |
| EP-1996320-A2 | METHODS AND APPARATUS FOR NEAR FIELD IRRADIATION | The President and Fellows of Harvard College (US) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007106402-A2 | METHODS AND APPARATUS FOR NEAR FIELD IRRADIATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2007-09-20 | — | — | WO | disclosed |