Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP3 | P08254 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2980552 | 1.00 | MMP1 (0.52) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL2988923 | 1.00 | MMP1 (0.52) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL14073842 | 0.82 | MMP1 (0.48) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL2982772 | 0.81 | — | — | |
| SCHEMBL4436649 | 0.81 | — | — | |
| SCHEMBL2984969 | 0.81 | — | — | |
| SCHEMBL2978621 | 0.80 | CA1 (0.41) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL2988176 | 0.80 | ELANE (0.38) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL4737399 | 0.80 | ELANE (0.38) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL4735804 | 0.80 | CA1 (0.41) | MMP1MMP2MMP3MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125702-A1 | LEVODOPA DIMETHYL-SUBSTITUTED DIESTER PRODRUGS, COMPOSITIONS, AND METHODS OF USE | Xenoport, Inc. (US) | 2009-12-02 | — | — | EP | claimed |
| WO-2008076458-A1 | LEVODOPA DIMETHYL-SUBSTITUTED DIESTER PRODRUGS, COMPOSITIONS, AND METHODS OF USE | XENOPORT, INC. (US) | 2008-06-26 | — | — | WO | claimed |