SCHEMBL4735804

SCHEMBL4735804

C[CH]C(C)OC(=O)CCC(C)C

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.41
LMNA P02545 2/20 0.34
MMP1 P03956 1/20 0.34
MMP2 P08253 1/20 0.34
MMP3 P08254 1/20 0.34
MMP9 P14780 1/20 0.34
MMP13 P45452 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
PTPN1 P18031 1/20 0.30
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2978621 1.00 CA1 (0.41) CA1LMNAMMP1MMP2MMP3
SCHEMBL2988077 1.00 CA1 (0.41) CA1LMNAMMP1MMP2MMP3
SCHEMBL2989642 0.81 ALDH1A1 (0.46) LMNAMMP1MMP2MMP3MMP9
SCHEMBL2980898 0.81 ALDH1A1 (0.46) LMNAMMP1MMP2MMP3MMP9
SCHEMBL4438952 0.81 ALDH1A1 (0.46) LMNAMMP1MMP2MMP3MMP9
SCHEMBL4445428 0.80 MMP1 (0.52) MMP1MMP2MMP3MMP9MMP13
SCHEMBL2980552 0.80 MMP1 (0.52) MMP1MMP2MMP3MMP9MMP13
SCHEMBL2988923 0.80 MMP1 (0.52) MMP1MMP2MMP3MMP9MMP13
SCHEMBL131802 0.78 LMNA (0.54) CA1LMNAMMP1MMP2MMP3
SCHEMBL2982657 0.78 LMNA (0.55) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008079387-A1 CATECHOL PROTECTED LEVODOPA DIESTER PRODRUGS, COMPOSITIONS, AND METHODS OF USE XENOPORT, INC. (US) 2008-07-03 WO disclosed