Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.49 |
| ▸ | RAB9A | P51151 | 7/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 2/20 | 0.35 |
| ▸ | YWHAG | P61981 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7268063 | 0.96 | NPC1 (0.46) | NPC1RAB9ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL30039355 | 0.88 | LMNA (0.36) | NPC1RAB9ALMNAALDH1A1KDM4E | |
| SCHEMBL4443214 | 0.87 | NPC1 (0.37) | NPC1RAB9ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL93485 | 0.87 | NPC1 (0.47) | NPC1RAB9ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL29358846 | 0.87 | NPC1 (0.47) | NPC1RAB9ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL4442083 | 0.87 | NPC1 (0.34) | NPC1RAB9ALMNAAPPYWHAG | |
| SCHEMBL29384829 | 0.87 | LMNA (0.35) | NPC1RAB9ALMNAALDH1A1KDM4E | |
| SCHEMBL105442 | 0.87 | LMNA (0.35) | NPC1RAB9ALMNAALDH1A1KDM4E | |
| SCHEMBL26489368 | 0.87 | NPC1 (0.48) | NPC1RAB9ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL30038851 | 0.86 | NPC1 (0.33) | NPC1RAB9ALMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1256611-B1 | Aqueous dispersion and coated product | JSR CORP (JP) | 2009-07-29 | — | — | EP | disclosed |
| US-6726997-B2 | WWATERPROOF, HARDNESS, RATION TRANSPARENT; PROTECTIVE COATINGS | JSR CORPORATION (JP) | 2004-04-27 | — | — | US | disclosed |
| US-20030073779-A1 | Aqueous dispersion and coated product | JSR CORPORATION (JP) | 2003-04-17 | — | — | US | disclosed |
| EP-1256611-A2 | Aqueous dispersion and coated product | JSR Corporation (JP) | 2002-11-13 | — | — | EP | disclosed |