SCHEMBL105442

SCHEMBL105442

C=C(C)C(=O)OCCc1ccc(O)c(-n2nc3ccc(Cl)cc3n2)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
RXFP1 Q9HBX9 1/20 0.35
APP P05067 3/20 0.34
YWHAG P61981 1/20 0.34
MAPT P10636 4/20 0.34
TP53 P04637 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
KDM4E B2RXH2 2/20 0.31
ALDH1A1 P00352 2/20 0.31
HPGD P15428 2/20 0.31
MCL1 Q07820 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
AKR1B1 P15121 1/20 0.31
IDE P14735 1/20 0.31
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29384829 1.00 LMNA (0.35) LMNANPC1RAB9ARXFP1APP
SCHEMBL29512642 0.94 TLR8 (0.34) LMNANPC1RAB9ARXFP1MAPT
SCHEMBL2775132 0.94 TLR8 (0.34) LMNANPC1RAB9ARXFP1MAPT
SCHEMBL1733769 0.92 MAPK1 (0.35) LMNANPC1RAB9ARXFP1MAPT
SCHEMBL30039355 0.90 LMNA (0.36) LMNANPC1RAB9AAPPYWHAG
SCHEMBL7268063 0.89 NPC1 (0.46) LMNANPC1RAB9AAPPYWHAG
SCHEMBL29358846 0.88 NPC1 (0.47) LMNANPC1RAB9AAPPYWHAG
SCHEMBL93485 0.88 NPC1 (0.47) LMNANPC1RAB9AAPPYWHAG
SCHEMBL29384278 0.87 MAPT (0.36) LMNANPC1RAB9AAPPYWHAG
SCHEMBL106982 0.87 MAPT (0.36) LMNANPC1RAB9AAPPYWHAG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 409 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3173826-B1 HYDROGEL COMPOSITION AND HYDROGEL CONTACT LENSES MADE OF THE COMPOSITION PEGAVISION CORP (TW) 2019-02-13 EP claimed
EP-3173826-A1 HYDROGEL COMPOSITION AND HYDROGEL CONTACT LENSES MADE OF THE COMPOSITION Pegavision Corporation (TW) 2017-05-31 EP claimed
US-9482788-B2 UV-blocking silicone hydrogel composition and silicone hydrogel contact lens containing thereof PEGAVISION CORPORATION (TW) 2016-11-01 US claimed
US-20160161638-A1 UV-BLOCKING SILICONE HYDROGEL COMPOSITION AND SILICONE HYDROGEL CONTACT LENS CONTAINING THEREOF PEGAVISION CORPORATION (TW) 2016-06-09 US claimed
EP-3029081-A1 Uv-blocking silicone hydrogel composition and silicone hydrogel contact lens containing thereof Pegavision Corporation (TW) 2016-06-08 EP claimed
US-7584630-B2 Photochromic ocular devices TRANSITIONS OPTICAL, INC. (US) 2009-09-08 US claimed
EP-1604231-B9 PHOTOCHROMIC OCULAR DEVICES TRANSITIONS OPTICAL INC (US) 2009-01-07 EP claimed
EP-1604231-B1 PHOTOCHROMIC OCULAR DEVICES TRANSITIONS OPTICAL INC (US) 2008-07-02 EP claimed
JP-2007524857-A 2007-08-30 JP claimed
US-20070113587-A1 Photochromic ocular devices TRANSITIONS OPTICAL LIMITED (IE) 2007-05-24 US claimed
EP-1604231-A1 PHOTOCHROMIC OCULAR DEVICES TRANSITIONS OPTICAL, INC. (US) 2005-12-14 EP claimed
WO-2004086103-A1 PHOTOCHROMIC OCULAR DEVICES TRANSITIONS OPTICAL INC. (US) 2004-10-07 WO claimed
US-20040186241-A1 Photochromic ocular devices TRANSITIONS OPTICAL, INC. 2004-09-23 US claimed
EP-0131468-B1 ULTRAVIOLET ABSORBING POLYMERS COMPRISING 2-HYDROXY-5-ACRYLYLOXALKYLPHENYL-2H-BENZOTRIAZOLES IOLAB CORPORATION (US) 1990-01-17 EP claimed
US-4528311-A Ultraviolet absorbing polymers comprising 2-hydroxy-5-acrylyloxyphenyl-2H-benzotriazoles IOLAB CORPORATION (US) 1985-07-09 US claimed
EP-0131468-A2 Ultraviolet absorbing polymers comprising 2-hydroxy-5-acrylyloxalkylphenyl-2H-benzotriazoles IOLAB CORPORATION (US) 1985-01-16 EP claimed
US-20260022221-A1 LAMINATE AND RESIN MOLDED BODY CONTAINING SAME KANEKA CORPORATION (JP) 2026-01-22 US disclosed
US-12479194-B2 Laminate TOYOBO CO., LTD. (JP) 2025-11-25 US disclosed
US-4889664-A MOLDING HYDROPHILIC (METH)ACRYLATE ESTER AND WATER DISPLACABLE BORIC ACID ESTER DILUENT VISTAKON, INC. (US) 1989-12-26 US disclosed
EP-0131468-A2 Ultraviolet absorbing polymers comprising 2-hydroxy-5-acrylyloxalkylphenyl-2H-benzotriazoles IOLAB CORPORATION (US) 1985-01-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260022221-A1 LAMINATE AND RESIN MOLDED BODY CONTAINING SAME MAP1LC3C, MAP1LC3B, MAP1LC3A LMNA 40/4885NPC1 3951/4885RAB9A 1988/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.