SCHEMBL4445467

SCHEMBL4445467

CCC1C(=O)CCCN1C

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.37
BRD2 P25440 1/20 0.37
ALOX5 P09917 2/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17866747 0.85 BRD4 (0.38) BRD4BRD2TSHR
SCHEMBL28216831 0.82 BRD4 (0.35) BRD4BRD2TSHR
SCHEMBL14682745 0.77 TSHR (0.54) BRD4BRD2TSHR
SCHEMBL692537 0.73 DRD2 (0.45)
SCHEMBL4970573 0.73 PIK3CD (0.31) TSHR
SCHEMBL2235440 0.71
SCHEMBL12045186 0.68 FGFR1 (0.34) TSHR
SCHEMBL6407688 0.68
SCHEMBL2231260 0.68 L3MBTL1 (0.42) ALOX5
SCHEMBL12025012 0.67 BRD4 (0.37) BRD4BRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090061267-A1 POWER DEVICE AND OXYGEN GENERATOR BATTELLE MEMORIAL INSTITUTE (US) 2009-03-05 US disclosed