Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 6/20 | 0.65 |
| ▸ | THRB | P10828 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | GSR | P00390 | 2/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11116780 | 0.86 | ALDH1A1 (0.72) | ALDH1A1TP53HIF1AHDAC3HDAC4 | |
| SCHEMBL9509983 | 0.84 | GSR (0.72) | THRATHRBGSR | |
| Hydrochloric Acid SCHEMBL10353476 | 0.82 | GSR (0.73) | THRATHRBGSR | |
| Hydrochloric Acid SCHEMBL1718491 | 0.81 | THRA (0.59) | THRATHRBTP53GSRHDAC3 | |
| SCHEMBL6687580 | 0.81 | HDAC3 (0.68) | ALDH1A1TP53HIF1AHDAC3HDAC4 | |
| SCHEMBL12855903 | 0.81 | ALDH1A1 (0.66) | ALDH1A1TP53HIF1AHDAC3HDAC4 | |
| SCHEMBL3527238 | 0.79 | ALDH1A1 (0.64) | ALDH1A1TP53HIF1AHDAC3HDAC4 | |
| SCHEMBL1718725 | 0.79 | ALDH1A1 (0.74) | ALDH1A1TP53HIF1AHDAC3HDAC4 | |
| SCHEMBL4937716 | 0.78 | ALDH1A1 (0.62) | THRATHRBALDH1A1TP53HIF1A | |
| SCHEMBL10290004 | 0.78 | ALDH1A1 (0.74) | THRBALDH1A1TP53HIF1AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090061267-A1 | POWER DEVICE AND OXYGEN GENERATOR | BATTELLE MEMORIAL INSTITUTE (US) | 2009-03-05 | — | — | US | disclosed |