Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3580835 | 0.84 | ALDH1A1 (0.39) | LIPEALDH1A1POLBL3MBTL1HTT | |
| SCHEMBL3580839 | 0.84 | ALDH1A1 (0.39) | LIPEALDH1A1POLBL3MBTL1HTT | |
| SCHEMBL3584213 | 0.84 | CETP (0.44) | ALDH1A1POLBL3MBTL1HTTCETP | |
| SCHEMBL3584208 | 0.84 | CETP (0.44) | ALDH1A1POLBL3MBTL1HTTCETP | |
| SCHEMBL3592622 | 0.83 | ALDH1A1 (0.39) | LIPEALDH1A1POLBL3MBTL1HTT | |
| SCHEMBL3592628 | 0.83 | ALDH1A1 (0.39) | LIPEALDH1A1POLBL3MBTL1HTT | |
| SCHEMBL4745885 | 0.82 | KMT2A (0.47) | ALDH1A1HTTCYP3A4CYP2C19NPSR1 | |
| SCHEMBL4439829 | 0.79 | ALDH1A1 (0.41) | LIPEALDH1A1POLBL3MBTL1HTT | |
| SCHEMBL3596633 | 0.78 | ALDH1A1 (0.39) | LIPEALDH1A1POLBL3MBTL1NPBWR1 | |
| SCHEMBL3596630 | 0.78 | ALDH1A1 (0.39) | LIPEALDH1A1POLBL3MBTL1NPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121598-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2009-11-25 | — | — | EP | claimed |
| WO-2008076754-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-06-26 | — | — | WO | claimed |