Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LIPE | Q05469 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4439090 | 0.89 | SCN9A (0.42) | ALDH1A1MAPTHTTLMNACYP3A4 | |
| SCHEMBL4439837 | 0.89 | SCN9A (0.42) | ALDH1A1MAPTHTTLMNACYP3A4 | |
| SCHEMBL4437663 | 0.89 | SCN9A (0.42) | ALDH1A1MAPTHTTLMNACYP3A4 | |
| SCHEMBL4439959 | 0.88 | SCN9A (0.38) | ALDH1A1POLBL3MBTL1LIPEMAPT | |
| SCHEMBL4439973 | 0.84 | PBRM1 (0.44) | ALDH1A1MAPTHTTLMNACYP3A4 | |
| SCHEMBL3580835 | 0.80 | ALDH1A1 (0.39) | ALDH1A1POLBL3MBTL1LIPEMAPT | |
| SCHEMBL3580839 | 0.80 | ALDH1A1 (0.39) | ALDH1A1POLBL3MBTL1LIPEMAPT | |
| SCHEMBL4445493 | 0.79 | LIPE (0.39) | ALDH1A1POLBL3MBTL1LIPEMAPT | |
| SCHEMBL4439891 | 0.78 | FNTA (0.38) | ALDH1A1MAPTHTTLMNACYP2C9 | |
| SCHEMBL4745885 | 0.78 | KMT2A (0.47) | ALDH1A1MAPTHTTCYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121598-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008076754-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-06-26 | — | — | WO | disclosed |