SCHEMBL4445596

SCHEMBL4445596

C=C(CC(C)N=C=O)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 4/20 0.42
TET3 O43151 1/20 0.42
TET1 Q8NFU7 1/20 0.42
GRIK1 P39086 1/20 0.41
GRIK2 Q13002 1/20 0.41
GRM1 Q13255 1/20 0.41
GRM2 Q14416 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4447284 0.81 TET2 (0.31) TET2TET3TET1GRIK1GRIK2
SCHEMBL10704558 0.81 TET2 (0.39) TET2TET3TET1GRIK1GRIK2
SCHEMBL2383532 0.79
SCHEMBL4630461 0.77
SCHEMBL7557897 0.75
SCHEMBL21715 0.71
SCHEMBL10709816 0.71
SCHEMBL14406993 0.69 TSHR (0.37)
Hydrochloric Acid SCHEMBL16756617 0.69 TET2 (0.52) TET2TET3TET1GRIK1GRIK2
SCHEMBL36381 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1474454-B1 THERMOSETTING COMPOSITIONS CONTAINING ALTERNATING COPOLYMERS OF ISOBUTYLENE TYPE MONOMERS PPG IND OHIO INC (US) 2009-11-18 EP claimed
EP-1474479-B1 POWDER COATING COMPOSITIONS HAVING IMPROVED MAR AND ACID RESISTANCE PPG IND OHIO INC (US) 2008-08-06 EP claimed
EP-0419043-B1 Thermosetting (meth)acrylate liquid resins and compositions containing them MITSUBISHI RAYON CO (JP) 1995-10-11 EP claimed
US-5442091-A Nonionic surfactant containing unsaturated carbamate monomers; thickeners NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1995-08-15 US claimed
US-5412142-A Unsaturated oxyalkylene carbamates, thickeners NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1995-05-02 US claimed
EP-0632083-A1 Novel associative monomers and polymers National Starch and Chemical Investment Holding Corporation (US) 1995-01-04 EP claimed
US-5294692-A Butylene oxide-ethylene oxide copolymers modified with isocyanatoalkyl acrylates for coatings, sizing, drilling fluid or detergents NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1994-03-15 US claimed
EP-1397390-B1 MODIFIED POLYMERS WITH A HIGH PROPORTION OF CIS-POSITION DOUBLE BONDS, METHOD FOR THE PRODUCTION AND USE THEREOF LANXESS DEUTSCHLAND GMBH (DE) 2008-01-09 EP disclosed
EP-1397390-A2 MODIFIED POLYMERS WITH A HIGH PROPORTION OF CIS-POSITION DOUBLE BONDS, METHOD FOR THE PRODUCTION AND USE THEREOF Bayer Aktiengesellschaft (DE) 2004-03-17 EP disclosed
WO-2002085952-A2 MODIFIED POLYMERS WITH A HIGH PROPORTION OF CIS-POSITION DOUBLE BONDS, METHOD FOR THE PRODUCTION AND USE THEREOF BAYER AKTIENGESELLSCHAFT (DE) 2002-10-31 WO disclosed
EP-0716103-B1 Polymerisable powder composition, flowable under pressure or under shearing IVOCLAR AG (LI) 1999-05-12 EP disclosed
US-5532036-A Methods for reducing volatile organic chemical contents of carpets NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1996-07-02 US disclosed
EP-0716103-A2 Polymerisable powder composition, flowable under pressure or under shearing IVOCLAR AG (LI) 1996-06-12 EP disclosed
US-5478881-A Unsaturated acids or esters, unsaturated carbamates; enhanced thickening efficiency NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1995-12-26 US disclosed
US-5442091-A Nonionic surfactant containing unsaturated carbamate monomers; thickeners NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1995-08-15 US disclosed
US-5412142-A Unsaturated oxyalkylene carbamates, thickeners NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1995-05-02 US disclosed
EP-0632083-A1 Novel associative monomers and polymers National Starch and Chemical Investment Holding Corporation (US) 1995-01-04 EP disclosed
US-5294692-A Butylene oxide-ethylene oxide copolymers modified with isocyanatoalkyl acrylates for coatings, sizing, drilling fluid or detergents NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1994-03-15 US disclosed
US-4552903-A Flexible polyurethane foams prepared from cotrimers of alkylene-bridged polyphenylene polyisocyanates THE DOW CHEMICAL COMPANY (US) 1985-11-12 US disclosed