⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1364812 | 0.79 | — | — | |
| SCHEMBL4445596 | 0.79 | TET2 (0.42) | — | |
| SCHEMBL29022284 | 0.77 | GABRP (0.46) | — | |
| SCHEMBL14406993 | 0.76 | TSHR (0.37) | — | |
| Hydrochloric Acid SCHEMBL11759753 | 0.76 | GABRP (0.45) | — | |
| SCHEMBL11577897 | 0.75 | SLC22A6 (0.39) | — | |
| SCHEMBL4630461 | 0.74 | — | — | |
| SCHEMBL3795396 | 0.74 | GSTK1 (0.42) | — | |
| SCHEMBL49404 | 0.73 | SLC22A6 (0.33) | — | |
| SCHEMBL11179643 | 0.73 | NAALAD2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210106690-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | MERSANA THERAPEUTICS, INC. | 2021-04-15 | — | — | US | disclosed |
| US-10603386-B2 | Protein-polymer-drug conjugates | MERSANA THERAPEUTICS, INC. (US) | 2020-03-31 | — | — | US | disclosed |
| EP-3330252-B1 | ISOPRENYL COMPOUNDS AND METHODS THEREOF | SIGNUM BIOSCIENCES INC (US) | 2020-02-12 | — | — | EP | disclosed |
| US-10314802-B2 | Isoprenyl compounds and methods thereof | SIGNUM BIOSCIENCES, INC. (US) | 2019-06-11 | — | — | US | disclosed |
| US-10226535-B2 | Auristatin compounds and conjugates thereof | MERSANA THERAPEUTICS, INC. (US) | 2019-03-12 | — | — | US | disclosed |
| EP-2928504-B1 | PROTEIN-POLYMER-DRUG CONJUGATES | MERSANA THERAPEUTICS INC (US) | 2019-02-20 | — | — | EP | disclosed |
| EP-2928503-B1 | CONJUGATES OF AURISTATIN COMPOUNDS | MERSANA THERAPEUTICS INC (US) | 2019-02-20 | — | — | EP | disclosed |
| US-20180243427-A1 | TUBULYSIN COMPOUNDS AND CONJUGATES THEREOF | MERSANA THERAPEUTICS, INC. | 2018-08-30 | — | — | US | disclosed |
| EP-3330252-A2 | ISOPRENYL COMPOUNDS AND METHODS THEREOF | Signum Biosciences, Inc. (US) | 2018-06-06 | — | — | EP | disclosed |
| EP-2963012-B1 | ISOPRENYL COMPOUNDS AND METHODS THEREOF | SIGNUM BIOSCIENCES INC (US) | 2018-01-10 | — | — | EP | disclosed |
| EP-1363900-B1 | ISOINDOLE-IMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | CELGENE CORP (US) | 2007-01-24 | — | — | EP | disclosed |
| US-7091353-B2 | Isoindole-imide compounds, compositions, and uses thereof | CELGENE CORPORATION (US) | 2006-08-15 | — | — | US | disclosed |
| US-20060025597-A1 | Isoindole-imide compounds, compositions, and uses thereof | CELGENE CORPORATION | 2006-02-02 | — | — | US | disclosed |
| EP-1363900-A1 | ISOINDOLE-IMIDE COMPOUNDS AS TNF-INHIBITORS | CELGENE CORPORATION (US) | 2003-11-26 | — | — | EP | disclosed |
| US-20030096841-A1 | Isoindole-imide compounds, compositions, and uses thereof | CELGENE CORPORATION | 2003-05-22 | — | — | US | disclosed |
| US-20030045552-A1 | Isoindole-imide compounds, compositions, and uses thereof | CELGENE CORPORATION | 2003-03-06 | — | — | US | disclosed |
| WO-2002059106-A1 | ISOINDOLE-IMIDE COMPOUNDS, COMPOSITIONS, AND USES THEREOF | CELGENE CORPORATION (US) | 2002-08-01 | — | — | WO | disclosed |
| EP-0348513-A1 | STYRENE DERIVATIVE, POLYSTYRENE DERIVATIVE COMPRISING THE SAME, PROCESS FOR PREPARING SAID POLYSTYRENE DERIVATIVE, AND ULTRAVIOLET ABSORBER COMPRISING SAID STYRENE DERIVATIVE OR POLYSTYRENE DERIVATIVE | EARTH CHEMICAL CO., LTD. (JP) | 1990-01-03 | — | — | EP | disclosed |
| EP-0152841-B1 | 6-Substituted-5-phenyltetrazolo[1,5-a][1,2,4]triazolo[1,5-c]pyrimidines | G.D. Searle & Co. (US) | 1988-07-27 | — | — | EP | disclosed |
| US-3949079-A | PLEUROMUTILIN; BACTERICIDES IN ANIMAL FEEDS | BIOCHEMIE GES.M.B.H. (OE) | 1976-04-06 | — | — | US | disclosed |