SCHEMBL4447284

SCHEMBL4447284

C=C(CCC(C)N=C=O)C(=O)O

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 3/20 0.31
TET3 O43151 1/20 0.31
TET1 Q8NFU7 1/20 0.31
GRIK1 P39086 1/20 0.31
GRIK2 Q13002 1/20 0.31
GRM1 Q13255 1/20 0.31
GRM2 Q14416 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10709816 0.82
SCHEMBL328919 0.81 TET2 (0.33) TET2TET3TET1GRIK1GRIK2
SCHEMBL4445596 0.81 TET2 (0.42) TET2TET3TET1GRIK1GRIK2
SCHEMBL29022284 0.80 GABRP (0.46) TET2TET3GRIK1GRIK2GRM1
SCHEMBL16353947 0.79
Hydrochloric Acid SCHEMBL11759753 0.79 GABRP (0.45) TET2TET3GRIK1GRIK2GRM1
SCHEMBL29011847 0.77
SCHEMBL3040262 0.75 TET2 (0.33) TET2TET3TET1GRIK1GRIK2
SCHEMBL11759743 0.75 TSHR (0.36)
SCHEMBL3238660 0.74 TET2 (0.39) TET2TET3TET1GRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1474454-B1 THERMOSETTING COMPOSITIONS CONTAINING ALTERNATING COPOLYMERS OF ISOBUTYLENE TYPE MONOMERS PPG IND OHIO INC (US) 2009-11-18 EP claimed
EP-1474479-B1 POWDER COATING COMPOSITIONS HAVING IMPROVED MAR AND ACID RESISTANCE PPG IND OHIO INC (US) 2008-08-06 EP claimed
EP-0201031-B1 (METH)ACRYLIC ESTERS AND THEIR USE BAYER AG (DE) 1989-08-02 EP disclosed
EP-0201031-A2 (Meth)acrylic esters and their use BAYER AG (DE) 1986-11-12 EP disclosed