Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Octane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.68 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.68 |
| ▸ | FDPS | P14324 | 11/20 | 0.59 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.59 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL11131007 | 1.00 | LPAR3 (0.68) | LPAR3LPAR2FDPSGGPS1LPAR1 | |
| Decane SCHEMBL5015979 | 1.00 | LPAR3 (0.68) | LPAR3LPAR2FDPSGGPS1LPAR1 | |
| Hexadecane SCHEMBL3437134 | 1.00 | LPAR3 (0.68) | LPAR3LPAR2FDPSGGPS1LPAR1 | |
| Dodecane SCHEMBL1262800 | 1.00 | LPAR3 (0.68) | LPAR3LPAR2FDPSGGPS1LPAR1 | |
| Phosphoric Acid SCHEMBL11052344 | 1.00 | LPAR3 (0.68) | LPAR3LPAR2FDPSGGPS1LPAR1 | |
| Decane SCHEMBL16986478 | 1.00 | LPAR3 (0.68) | LPAR3LPAR2FDPSGGPS1LPAR1 | |
| Octane SCHEMBL9461155 | 1.00 | LPAR3 (0.68) | LPAR3LPAR2FDPSGGPS1LPAR1 | |
| Dodecane SCHEMBL11581918 | 1.00 | LPAR3 (0.68) | LPAR3LPAR2FDPSGGPS1LPAR1 | |
| Octane SCHEMBL21854612 | 1.00 | LPAR3 (0.68) | LPAR3LPAR2FDPSGGPS1LPAR1 | |
| Octane SCHEMBL3458550 | 1.00 | LPAR3 (0.68) | LPAR3LPAR2FDPSGGPS1LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3947522-B1 | PROCESS FOR PROVIDING A HOMOGENEOUS POLYETHER POLYOL COMPOSITION, REACTION MIXTURE COMPRISING A COMPOSITION OBTAINED BY THE PROCESS, AND POLYURETHANE PRODUCTS OBTAINED FROM THE REACTION MIXTURE | HUNTSMAN INT LLC (US) | 2025-10-15 | — | — | EP | claimed |
| US-12187839-B2 | Polyether polyol | HUNTSMAN INTERNATIONAL LLC | 2025-01-07 | — | — | US | claimed |
| US-20220135730-A1 | POLYETHER POLYOL | HUNTSMAN INTERNATIONAL LLC | 2022-05-05 | — | — | US | claimed |
| EP-3947522-A1 | POLYETHER POLYOL | Huntsman International LLC (US) | 2022-02-09 | — | — | EP | claimed |
| WO-2020193087-A1 | POLYETHER POLYOL | HUNTSMAN INTERNATIONAL LLC (US) | 2020-10-01 | — | — | WO | claimed |
| EP-3947522-B1 | PROCESS FOR PROVIDING A HOMOGENEOUS POLYETHER POLYOL COMPOSITION, REACTION MIXTURE COMPRISING A COMPOSITION OBTAINED BY THE PROCESS, AND POLYURETHANE PRODUCTS OBTAINED FROM THE REACTION MIXTURE | HUNTSMAN INT LLC (US) | 2025-10-15 | — | — | EP | disclosed |
| CN-119775193-A | Rafenacin triphenyl acetate and powder inhalation thereof | 山东京卫制药有限公司 | 2025-04-08 | — | — | CN | disclosed |
| CN-119775192-A | Triphenylacetic acid Lei Fen-sodium octyl crystal form and preparation method thereof | 山东京卫制药有限公司 | 2025-04-08 | — | — | CN | disclosed |
| US-12187839-B2 | Polyether polyol | HUNTSMAN INTERNATIONAL LLC | 2025-01-07 | — | — | US | disclosed |
| EP-3947522-A1 | POLYETHER POLYOL | Huntsman International LLC (US) | 2022-02-09 | — | — | EP | disclosed |
| WO-2020193087-A1 | POLYETHER POLYOL | HUNTSMAN INTERNATIONAL LLC (US) | 2020-10-01 | — | — | WO | disclosed |
| EP-1720937-A4 | CELLULOSE ACYLATE FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY | FUJIFILM CORP (JP) | 2009-05-27 | — | — | EP | disclosed |
| US-20070172605-A1 | Cellulose acylate film, polarizing plate and liquid crystal display | FUJI PHOTO FILM CO., LTD. (JP) | 2007-07-26 | — | — | US | disclosed |
| EP-1720937-A1 | CELLULOSE ACYLATE FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY | FUJI PHOTO FILM CO., LTD. (JP) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005080482-A1 | CELLULOSE ACYLATE FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY | FUJI PHOTO FILM CO., LTD. (JP) | 2005-09-01 | — | — | WO | disclosed |
| EP-0113454-B1 | EXTRACTION OF SILVER AND PALLADIUM METALS FROM AQUEOUS SOLUTIONS USING TERTIARY PHOSPHINE SULFIDES | AMERICAN CYANAMID COMPANY (US) | 1987-02-04 | — | — | EP | disclosed |
| US-4623522-A | COMPLEXING | AMERICAN CYANAMID COMPANY (US) | 1986-11-18 | — | — | US | disclosed |
| EP-0113454-A2 | Extraction of silver and palladium metals from aqueous solutions using tertiary phosphine sulfides | AMERICAN CYANAMID COMPANY (US) | 1984-07-18 | — | — | EP | disclosed |