Oxirane

Oxirane

SCHEMBL4445778

C1CO1.CCCCCCCCCCCC(=O)NCC(O)O

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FAAH O00519 7/20 0.55
ASAH1 Q13510 1/20 0.52
MEN1 O00255 1/20 0.47
MAPK1 P28482 1/20 0.47
KMT2A Q03164 1/20 0.47
HSP90AA1 P07900 1/20 0.47
DNM1 Q05193 2/20 0.46
CASP2 P42575 1/20 0.44
NOD1 Q9Y239 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28125168 0.91 FAAH (0.64) FAAHASAH1MEN1MAPK1KMT2A
SCHEMBL4358198 0.91 FAAH (0.64) FAAHASAH1MEN1MAPK1KMT2A
SCHEMBL28713712 0.91 FAAH (0.64) FAAHASAH1MEN1MAPK1KMT2A
SCHEMBL27546913 0.91 FAAH (0.64) FAAHASAH1MEN1MAPK1KMT2A
SCHEMBL11344717 0.89 FAAH (0.61) FAAHASAH1MEN1MAPK1KMT2A
SCHEMBL11328643 0.84 FAAH (0.52) FAAHASAH1MEN1MAPK1KMT2A
SCHEMBL6553246 0.82 EPHX2 (0.61) FAAHMEN1KMT2A
SCHEMBL936696 0.82 EPHX2 (0.61) FAAHMEN1KMT2A
SCHEMBL19987660 0.82 EPHX2 (0.61) FAAHMEN1KMT2A
SCHEMBL6361669 0.80 FAAH (0.64) FAAHASAH1MEN1MAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090264578-A1 Aggregation-preventive aqueous dispersion slurry coating material and process for producing the same SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2009-10-22 US disclosed